Antibodies are proteins that recognize the molecular surfaces of potentially noxious
molecules to mount an adaptive immune response or, in the case of autoimmune diseases …

The role in human health of therapeutic proteins in general, and monoclonal antibodies
(mAbs) in particular, has been significant and is continuously evolving. A considerable …

Pulmonary administration route has been extensively exploited for the treatment of local
lung diseases such as asthma, chronic obstructive pulmonary diseases and respiratory …

Protein stability against aggregation is a major quality concern for the production of safe and
effective biopharmaceuticals. Amongst the different drivers of protein aggregation …

Therapeutic proteins provide interventions for some of the most complex and intractable
diseases and are an essential part of modern medicine. Immunogenicity is the development …

The safety and efficacy of protein pharmaceuticals depend not only on biological activity but
also on purity levels. Impurities may be process related because of limitations in …

Detection and characterization of particles in the visible and subvisible size range is critical
in many fields of industrial research. Commercial particle analysis systems have proliferated …

ABSTRACT A major impediment to successful use of therapeutic protein drugs is their ability
to induce anti-drug antibodies (ADA) that can alter treatment efficacy and safety in a …

Proteins and peptides-based therapeutics are making substantial access to the market due
to their obvious advantages of strong potency, high specificity and desirable safety profile …

The biosafety of sericin remains controversial. The misunderstanding regarding sericin
causing adverse biological responses have been clarified by extensively reviewing relevant …