Background. Africa still bears the largest burden of malaria as the majority of infections in the
continent are caused by P. falciparum. Artemether‐lumefantrine (AL, Coartem®) is the most …

Malaria affects millions of people annually, especially in third-world countries. The mainstay
of treatment is oral anti-malarial drugs and vaccination. An increase in resistant strains of …

Background and Purpose The artemisinin derivative, artemether, has antimalarial activity
with potential neurotoxic and cardiotoxic effects. Artemether in nanocapsules (NC‐ATM) is …

Malaria remains a major public health issue in Nigeria, and Nigeria is one of the main
sources of imported malaria in China. Antimalarial drug resistance is a significant obstacle to …

Background Herbal medicine has been a rich source of new drugs exemplified by quinine
and artemisinin. In this study, a variety of Japanese traditional herbal medicine ('Kampo') …

Background Recent reports of artemisinin partial resistance from Rwanda and Uganda are
worrisome and suggest a future policy change to adopt new anti-malarials. This is a case …

Background Plasmodium falciparum, the deadliest causative agent of malaria, has high
prevalence in Nigeria. Drug resistance causing failure of previously effective drugs has …

Background The development and spread of artemisinin-resistant Plasmodium falciparum
malaria in Greater Mekong Subregion has created impetus for continuing global monitoring …

Background Artemisinin-based combination therapies (ACTs) have remained efficacious
treatments of acute falciparum malaria in many endemic areas but there is little evaluation of …

疟疾是一种严重危及生命的传染病, 对人类生活产生着深远影响. 青蒿素至今仍是世界卫生组织
推荐的临床抗疟一线用药, 其抗疟活性主要体现在过氧桥结构上. 以青蒿素类化合物为基础的 …