Tumor dormancy: implications for invasion and metastasis
Tumor dormancy refers to a critical stage of cancer development when tumor cells are
present, but cancer does not progress. It includes both the concept of cellular dormancy …
present, but cancer does not progress. It includes both the concept of cellular dormancy …
Predicting the response to neoadjuvant therapy for early-stage breast cancer: tumor-, blood-, and imaging-related biomarkers
W Tan, M Yang, H Yang, F Zhou… - Cancer management and …, 2018 - Taylor & Francis
Neoadjuvant therapy (NAT) has been used increasingly in patients with locally advanced or
early-stage breast cancer. However, the accurate evaluation and prediction of response to …
early-stage breast cancer. However, the accurate evaluation and prediction of response to …
Stromal-initiated changes in the bone promote metastatic niche development
More than 85% of advanced breast cancer patients suffer from metastatic bone lesions, yet
the mechanisms that facilitate these metastases remain poorly understood. Recent studies …
the mechanisms that facilitate these metastases remain poorly understood. Recent studies …
Clinical outcome with correlation to disseminated tumor cell (DTC) status after DTC-guided secondary adjuvant treatment with docetaxel in early breast cancer
B Naume, M Synnestvedt, RS Falk… - Journal of Clinical …, 2014 - ascopubs.org
Purpose The presence of disseminated tumor cells (DTCs) in bone marrow (BM) predicts
survival in early breast cancer. This study explores the use of DTCs for identification of …
survival in early breast cancer. This study explores the use of DTCs for identification of …
Circulating and disseminated tumor cells from breast cancer patient-derived xenograft-bearing mice as a novel model to study metastasis
M Giuliano, S Herrera, P Christiny, C Shaw… - Breast cancer …, 2015 - Springer
Introduction Real-time monitoring of biologic changes in tumors may be possible by
investigating the transitional cells such as circulating tumor cells (CTCs) and disseminated …
investigating the transitional cells such as circulating tumor cells (CTCs) and disseminated …
Persistence of disseminated tumor cells after neoadjuvant treatment for locally advanced breast cancer predicts poor survival
RR Mathiesen, E Borgen, A Renolen, E Løkkevik… - Breast Cancer …, 2012 - Springer
Introduction Presence of disseminated tumor cells (DTCs) in bone marrow (BM) and
circulating tumor cells (CTC) in peripheral blood (PB) predicts reduced survival in early …
circulating tumor cells (CTC) in peripheral blood (PB) predicts reduced survival in early …
Deciphering the increased prevalence of TP53 mutations in metastatic prostate cancer
The prevalence of TP53 mutations in advanced prostate cancers (PCa) is 3 to 5 times of the
quantity in primary PCa. By an integrative analysis of the Cancer Genome Atlas and …
quantity in primary PCa. By an integrative analysis of the Cancer Genome Atlas and …
Biomarkers of residual disease, disseminated tumor cells, and metastases in the MMTV-PyMT breast cancer model
Cancer metastases arise in part from disseminated tumor cells originating from the primary
tumor and from residual disease persisting after therapy. The identification of biomarkers on …
tumor and from residual disease persisting after therapy. The identification of biomarkers on …
[HTML][HTML] Clinical relevance of cancer stem cells in bone marrow of early breast cancer patients
Abstract Background Cancer stem cells (CSCs) are epithelial tumor cells that express
CD44+ CD24-/lo. CSCs can be further divided into those that have aldehyde …
CD44+ CD24-/lo. CSCs can be further divided into those that have aldehyde …
Outcomes and clinicopathologic characteristics associated with disseminated tumor cells in bone marrow after neoadjuvant chemotherapy in high-risk early stage …
MJM Magbanua, L van 't Veer, AS Clark… - Breast cancer research …, 2023 - Springer
Abstract Purpose Disseminated tumor cells (DTCs) expressing epithelial markers in the
bone marrow are associated with recurrence and death, but little is known about risk factors …
bone marrow are associated with recurrence and death, but little is known about risk factors …