The molecular mechanisms of the metabolism and transport of iron in normal and neoplastic cells
DR Richardson, P Ponka - Biochimica Et Biophysica Acta (BBA)-Reviews …, 1997 - Elsevier
Virtually all living cells possess an absolute re-Ž. quirement for iron Fe, and it has been
suggested that reactions catalyzed by Fe may have constituted a wx first step in the origin of …
suggested that reactions catalyzed by Fe may have constituted a wx first step in the origin of …
[HTML][HTML] Human transferrin: An inorganic biochemistry perspective
AMN Silva, T Moniz, B de Castro, M Rangel - Coordination Chemistry …, 2021 - Elsevier
Transferrin (Tf) is an essential protein, probably ubiquitous to all metazoans. The main
function of this family of proteins is to bind and transport ferric ions, increasing Fe (III) …
function of this family of proteins is to bind and transport ferric ions, increasing Fe (III) …
Transferrin receptors in human tissues: their distribution and possible clinical relevance.
KC Gatter, G Brown, IS Trowbridge… - Journal of clinical …, 1983 - jcp.bmj.com
The distribution of transferrin receptors (TR) has been studied in a range of normal and
malignant tissues using four monoclonal antibodies, BK19. 9, B3/25, T56/14 and T58/1. In …
malignant tissues using four monoclonal antibodies, BK19. 9, B3/25, T56/14 and T58/1. In …
Tumor targeting based on the effect of enhanced permeability and retention (EPR) and the mechanism of receptor-mediated endocytosis (RME)
T Tanaka, S Shiramoto, M Miyashita… - International journal of …, 2004 - Elsevier
This review is focused on the macromolecular drug carrier systems by the effect of enhanced
permeability and retention (EPR) and the mechanism of receptor-mediated endocytosis …
permeability and retention (EPR) and the mechanism of receptor-mediated endocytosis …
The effect of the iron saturation of transferrin on its binding and uptake by rabbit reticulocytes
SP Young, A Bomford, R Williams - Biochemical Journal, 1984 - portlandpress.com
Polyacrylamide-gel electrophoresis in urea was used to prepare the four molecular species
of transferrin: diferric transferrin, apotransferrin and the two monoferric transferrins with …
of transferrin: diferric transferrin, apotransferrin and the two monoferric transferrins with …
Novel 3-hydroxy-2 (1H)-pyridinones. Synthesis, iron (III)-chelating properties and biological activity
M Streater, PD Taylor, RC Hider… - Journal of Medicinal …, 1990 - ACS Publications
The synthesis of a range of novel bidentate and hexadentate ligands containing the
chelating moiety 3-hydroxy-2 (l/i)-pyridinone is described. The pK, values of the ligands and …
chelating moiety 3-hydroxy-2 (l/i)-pyridinone is described. The pK, values of the ligands and …
Interactions between isolated hepatocytes and Kupffer cells in iron metabolism: a possible role for ferritin as an iron carrier protein
JC Sibille, H Kondo, P Aisen - Hepatology, 1988 - journals.lww.com
Like the rat peritoneal macrophage, the isolated Kupffer cell is capable of processing and
releasing iron acquired by phagocytosis of immunosensitized homologous red blood cells …
releasing iron acquired by phagocytosis of immunosensitized homologous red blood cells …
Iron metabolism in the erythrophagocytosing Kupffer cell
H Kondo, K Saito, JP Grasso, P Aisen - Hepatology, 1988 - journals.lww.com
Like the peritoneal macrophage, the isolated Kupffer cell is capable of processing and
releasing iron acquired by phagocytosis of immunosensitized homologous red blood cells …
releasing iron acquired by phagocytosis of immunosensitized homologous red blood cells …
Iron mobilization from hepatocyte monolayer cultures by chelators: the importance of membrane permeability and the iron-binding constant
JB Porter, M Gyparaki, LC Burke, ER Huehns… - 1988 - ashpublications.org
A series of bidentate hydroxypyridinone iron chelators that have therapeutic potential as oral
iron chelators, have been studied systematically to determine which properties are the most …
iron chelators, have been studied systematically to determine which properties are the most …
[PDF][PDF] Transferrin receptor‐independent uptake of differic transferrin by human hepatoma cells with antisense inhibition of receptor expression
D Trinder, O Zak, P Aisen - Hepatology, 1996 - Wiley Online Library
The hepatic uptake of transferrin‐bound iron by a nontransferrin receptor (NTR)‐mediated
process was investigated using the human hepatoma cell line HuH7. Because HuH7 cells …
process was investigated using the human hepatoma cell line HuH7. Because HuH7 cells …