Allenes are a class of unique compounds with two π-orbitals perpendicular to each other.
The first synthesis can be traced back to 1887. 1 They also exist in many natural products …

There are still some synthetic chemists who hesitate to use metal-mediated or-catalysed
reactions. The Pauson–Khand reaction (PKR) is a powerful transformation that has now …

Covering: 2000–2018 In this review, we highlight recent examples of natural product total
syntheses employing transition metal-mediated/catalyzed carbonylative cyclization …

The [2+ 2+ 1] cyclization of an alkyne, an alkene and carbon monoxide, ie, the Pauson–
Khand reaction, is one of the most powerful tools for constructing a five-membered ring. In …

Treatment of alkynyl allenes with [Rh (CO) 2Cl] 2 results in a formal [2+ 2+ 1] cycloaddition
reaction. This reaction occurs with complete regioselectivity for a variety of substrates …

(AOR) or leukotriene B4 12-hydroxydehydrogenase, reductively activates AFs. 54 AFs
interact with redox-modulating enzymes, such as glutathione reductase (GR), thioredoxin …

Allenes have emerged as increasingly popular intermediates for asymmetric organic
synthesis due largely to the potential for relaying the associated axial chirality to ensuing …

The first synthesis of functionalized gem-difluoroallenes 4 served as platform for an
unprecedented molybdenum-catalyzed intramolecular allene-alkyne [2+ 2]-cycloaddition …

The first total synthesis of sespenine, a rare indole sesquiterpenoid from a mangrove
endophyte, has been accomplished. A bioinspired aza‐Prins/Friedel–Crafts/retro Friedel …

Herein we describe a novel Co2 (CO) 8-catalyzed intramolecular aza-Pauson− Khand-type
reaction of alkynecarbodiimide derivatives affords pyrrolo [2, 3-b] indol-2-one ring systems in …