Although present conventional foot-and-mouth disease (FMD) vaccines can prevent clinical
disease, protection is short lived (∼ 6 months), often requiring frequent revaccination for …

Viral infectious diseases pose a serious threat to animal husbandry, especially in the pig
industry. With the rapid, continuous variation of viruses, a series of therapeutic measures …

Picornavirus infection can lead to disruption of nuclear pore traffic, shut-off of cell translation
machinery, and cleavage of proteins involved in cellular signal transduction and the innate …

Inactivated foot-and-mouth disease (FMD) vaccines are currently used worldwide. With the
emergence of various FMD virus serotypes and subtypes, vaccines must become more …

Background Plant viruses can be employed as versatile vectors for the production of
vaccines by expressing immunogenic epitopes on the surface of chimeric viral particles …

Background This study was performed to assess the knowledge, attitudes and practices
(KAPs) of farmers and veterinary professionals towards foot‐and‐mouth disease (FMD) in …

Cap-independent translation initiation on picornavirus mRNAs is mediated by an internal
ribosomal entry site (IRES) in the 5′ untranslated region. The regulation of internal initiation …

The RNA helicase LGP2 (Laboratory of Genetics and Physiology 2) is a non-signaling
member of the retinoic acid-inducible gene-I (RIG-I)-like receptors (RLRs), whose pivotal …

Pseudorabies virus (PRV) is a double‐stranded, DNA‐based swine virus with a genome
approximating 150 kb in size. PRV has many nonessential genes which can be replaced …

Calcium phosphate nanoparticles provide safe and easily manufactured vaccine adjuvant
and delivery system for DNA vaccines. In the present study FMDV “O” P1-3CD DNA vaccine …