[HTML][HTML] HPV infections—classification, pathogenesis, and potential new therapies

B Mlynarczyk-Bonikowska, L Rudnicka - International Journal of …, 2024 - mdpi.com
To date, more than 400 types of human papillomavirus (HPV) have been identified. Despite
the creation of effective prophylactic vaccines against the most common genital HPVs, the …

The human papillomavirus late life cycle and links to keratinocyte differentiation

A Kirk, SV Graham - Journal of Medical Virology, 2024 - Wiley Online Library
Regulation of human papillomavirus (HPV) gene expression is tightly linked to differentiation
of the keratinocytes the virus infects. HPV late gene expression is confined to the cells in the …

HPV E6 inhibits E6AP to regulate epithelial homeostasis by modulating keratinocyte differentiation commitment and YAP1 activation

W Yin, N Egawa, K Zheng, H Griffin, P Tian… - PLoS …, 2023 - journals.plos.org
Human papillomaviruses (HPV) cause persistent infections by modulating epithelial
homeostasis in cells of the infected basal layer. Using FUCCI and cell-cell competition …

It takes two to tango: a review of oncogenic virus and host microbiome associated Inflammation in head and neck cancer

MG McKeon, JN Gallant, YJ Kim, SR Das - Cancers, 2022 - mdpi.com
Simple Summary Certain viruses, specifically, human papillomavirus (HPV) and Epstein–
Barr virus (EBV), have been linked with the development of head and neck cancer. In this …

[HTML][HTML] The antiviral effects of a MEK1/2 inhibitor promote tumor regression in a preclinical model of human papillomavirus infection-induced tumorigenesis

AJ Luna, JM Young, RT Sterk, V Bondu, FA Schultz… - Antiviral Research, 2023 - Elsevier
Human papillomaviruses (HPVs) are a significant public health concern due to their
widespread transmission, morbidity, and oncogenic potential. Despite efficacious vaccines …

The significance of nonsurgical therapies for cervical infection of high‐risk human papilloma virus: A systematic review and meta‐analysis

Y Zhuang, H Yang - Journal of Obstetrics and Gynaecology …, 2023 - Wiley Online Library
Objective To assess whether nonsurgical therapies were related with clearance of cervical
infection of high‐risk human papilloma virus (hr‐HPV) or regression of mild abnormal …

PAD-mediated citrullination is a novel candidate diagnostic marker and druggable target for HPV-associated cervical cancer

C Albano, M Biolatti, J Mazibrada… - Frontiers in Cellular …, 2024 - frontiersin.org
Citrullination is an emerging post-translational modification catalyzed by peptidyl-arginine
deiminases (PADs) that convert peptidyl-arginine into peptidyl-citrulline. In humans, the PAD …

Acquisition of genetic aberrations during the progression of high-grade intraepithelial lesions/micro-invasive squamous cancers to widely invasive cervical squamous …

K Kashofer, O Reich, S Regauer - Archives of Pathology & …, 2023 - meridian.allenpress.com
Context.—Acquisition of genetic aberrations during cervical carcinogenesis in individual
patients is poorly documented. Objective.—To provide a comparative analysis of high-grade …

The cutaneous beta human papillomavirus type 8 E6 protein induces CCL2 through the CEBPα/miR-203/p63 pathway to support an inflammatory microenvironment in …

L Vella, A Sternjakob, S Lohse, A Fingerle… - Frontiers in Cellular …, 2024 - frontiersin.org
Human papillomavirus type 8 (HPV8), a cutaneous genus beta HPV type, has co-
carcinogenic potential at sun-exposed sites in patients suffering from the inherited skin …

Detecting and genotyping high-risk human papillomavirus among male patients during 2015–2023 in Beijing, China

S Wang, QY Ma, J Du, TT Wei, WX Zhang… - Emerging Microbes & …, 2024 - Taylor & Francis
Few studies focused on human papillomavirus (HPV) in male patients. This study aimed to
explore the detection rate and genotyping of HPV among male patients in Beijing to provide …