Cerebral oxygen extraction fraction MRI: Techniques and applications

D Jiang, H Lu - Magnetic resonance in medicine, 2022 - Wiley Online Library
The human brain constitutes 2% of the body's total mass but uses 20% of the oxygen. The
rate of the brain's oxygen utilization can be derived from a knowledge of cerebral blood flow …

[HTML][HTML] Cerebral oxygen metabolism from MRI susceptibility

E Biondetti, J Cho, H Lee - Neuroimage, 2023 - Elsevier
This article provides an overview of MRI methods exploiting magnetic susceptibility
properties of blood to assess cerebral oxygen metabolism, including the tissue oxygen …

Cluster analysis of time evolution (CAT) for quantitative susceptibility mapping (QSM) and quantitative blood oxygen level‐dependent magnitude (qBOLD)‐based …

J Cho, S Zhang, Y Kee, P Spincemaille… - Magnetic resonance …, 2020 - Wiley Online Library
Purpose To improve the accuracy of QSM plus quantitative blood oxygen level‐dependent
magnitude (QSM+ qBOLD or QQ)‐based mapping of the oxygen extraction fraction (OEF) …

Validation of a new 3D quantitative BOLD based cerebral oxygen extraction mapping

H Lee, J Xu, MA Fernandez-Seara… - Journal of Cerebral …, 2024 - journals.sagepub.com
Quantitative BOLD (qBOLD) MRI allows evaluation of oxidative metabolism of the brain
based purely on an endogenous contrast mechanism. The method quantifies deoxygenated …

QQ‐NET–using deep learning to solve quantitative susceptibility mapping and quantitative blood oxygen level dependent magnitude (QSM+ qBOLD or QQ) based …

J Cho, J Zhang, P Spincemaille… - Magnetic resonance …, 2022 - Wiley Online Library
Purpose To improve accuracy and speed of quantitative susceptibility mapping plus
quantitative blood oxygen level‐dependent magnitude (QSM+ qBOLD or QQ)‐based …

[HTML][HTML] Whole-brain 3D mapping of oxygen metabolism using constrained quantitative BOLD

H Lee, FW Wehrli - Neuroimage, 2022 - Elsevier
Abstract Quantitative BOLD (qBOLD) MRI permits noninvasive evaluation of hemodynamic
and metabolic states of the brain by quantifying parametric maps of deoxygenated blood …

Temporal clustering, tissue composition, and total variation for mapping oxygen extraction fraction using QSM and quantitative BOLD

J Cho, P Spincemaille, TD Nguyen… - Magnetic resonance …, 2021 - Wiley Online Library
Purpose To improve the accuracy of quantitative susceptibility mapping plus quantitative
blood oxygen level‐dependent magnitude (QSM+ qBOLD or QQ) based mapping of oxygen …

Measurement of cerebral oxygen extraction fraction using quantitative BOLD approach: A review

H Li, C Wang, X Yu, Y Luo, H Wang - Phenomics, 2023 - Springer
Quantification of brain oxygenation and metabolism, both of which are indicators of the level
of brain activity, plays a vital role in understanding the cerebral perfusion and the …

Calibrated fMRI for dynamic mapping of CMRO2 responses using MR-based measurements of whole-brain venous oxygen saturation

EK Englund, MA Fernández-Seara… - Journal of Cerebral …, 2020 - journals.sagepub.com
Functional MRI (fMRI) can identify active foci in response to stimuli through BOLD signal
fluctuations, which represent a complex interplay between blood flow and cerebral …

Venous cerebral blood volume mapping in the whole brain using venous‐spin‐labeled 3D turbo spin echo

H Lee, FW Wehrli - Magnetic Resonance in Medicine, 2020 - Wiley Online Library
Purpose Venous cerebral blood volume (CBVv) is a major contributor to BOLD contrast, and
therefore is an important parameter for understanding the underlying mechanism. Here, we …