Trace metals are essential micronutrients required for survival across all kingdoms of life.
From bacteria to animals, metals have critical roles as both structural and catalytic cofactors …

Nutritional immunity is a form of innate immunity widespread in both vertebrates and
invertebrates. The term refers to a rich repertoire of mechanisms set up by the host to inhibit …

Hendra virus and Nipah virus (NiV), members of the Henipavirus (HNV) genus, are zoonotic
paramyxoviruses known to cause severe disease across six mammalian orders, including …

Host-directed therapy (HDT) is an emerging approach to overcome antimicrobial resistance
in pathogenic microorganisms. Specifically, HDT targets host-encoded factors required for …

Heme, an iron-containing tetrapyrrole in hemoproteins, including: hemoglobin, myoglobin,
catalase, cytochrome c, and cytochrome P450, plays critical physiological roles in different …

The opportunistic pathogen Staphylococcus aureus has become a major threat for human
health and well-being by developing resistance to antibiotics and by fast evolution into new …

Although computational structure prediction has had great successes in recent years, it
regularly fails to predict the interactions of large protein complexes with residue-level …

Staphylococcus aureus is an important human pathogen that infects nearly every human
tissue. Like most organisms, the acquisition of nutrient iron is necessary for its survival. One …

Host-directed therapy (HDT) is an emerging approach to overcome antimicrobial resistance
in pathogenic microorganisms. Specifically, HDT targets host-encoded factors required for …

Staphylococcus aureus is a serious threat to public health due to the rise of antibiotic
resistance in this organism, which can prolong or exacerbate skin and soft tissue infections …