Perspectives and mechanisms for targeting mitotic catastrophe in cancer treatment

Z Bai, Y Zhou, Y Peng, X Ye, L Ma - … et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
Mitotic catastrophe is distinct from other cell death modes due to unique nuclear alterations
characterized as multi and/or micronucleation. Mitotic catastrophe is a common and virtually …

Allosteric activation of protein phosphatase 5 with small molecules

Q Zhang, L Yan, L Zhang, J Yu, Z Han… - Journal of Medicinal …, 2024 - ACS Publications
The activation of PP5 is essential for a variety of cellular processes, as it participates in a
variety of biological pathways by dephosphorylating substrates. However, activation of PP5 …

Polo-like kinase 4 promotes tumorigenesis and glucose metabolism in glioma by activating AKT1 signaling

B Wang, X Zhang, Z Li, C Wei, R Yu, X Du, Y He, Y Ren… - Cancer Letters, 2024 - Elsevier
Glioblastoma (GBM) is an extremely aggressive tumor associated with a poor prognosis that
impacts the central nervous system. Increasing evidence suggests an inherent association …

A PP4 foszfatáz és a Centrobin kapcsolata a DNS hibajavítás késői szakaszaiban

RN Zsuzsánna - 2023 - search.proquest.com
2. ábra. A fehérje foszfatázok csoportosítása. Az alapján, hogy a szubsztrátum mely
aminosaváról távolítják el a foszfát csoportot, két nagy családot különítünk el: Tyr foszfatázok …