[HTML][HTML] Hepatic stellate cells: dictating outcome in nonalcoholic fatty liver disease

L Wiering, P Subramanian, L Hammerich - Cellular and Molecular …, 2023 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is a fast growing, chronic liver disease affecting∼
25% of the global population. Nonalcoholic fatty liver disease severity ranges from the less …

Obesity, non-alcoholic fatty liver disease and hepatocellular carcinoma: Current status and therapeutic targets

Y Chen, W Wang, MP Morgan, T Robson… - Frontiers in …, 2023 - frontiersin.org
Obesity is a global epidemic and overwhelming evidence indicates that it is a risk factor for
numerous cancers, including hepatocellular carcinoma (HCC), the third leading cause of …

Integrated miRNA-mRNA analysis reveals the dysregulation of lipid metabolism in mouse liver induced by developmental arsenic exposure

X Chen, R Wu, H Wu, Y Hu, H Wang, J Fu, J Pi… - Journal of Hazardous …, 2023 - Elsevier
Developmental arsenic exposure leads to increased susceptibility to liver diseases including
nonalcoholic fatty liver diseases, but the mechanism is incompletely understood. In this …

Moringa oleifera Improves MAFLD by Inducing Epigenetic Modifications

CA Monraz-Méndez, R Escutia-Gutiérrez… - Nutrients, 2022 - mdpi.com
Background and aims. Metabolic Associated Fatty Liver Disease (MAFLD) encompasses a
spectrum of diseases from simple steatosis to nonalcoholic steatohepatitis (NASH). Here, we …

An update in epigenetics in metabolic-associated fatty liver disease

JS Rodríguez-Sanabria, R Escutia-Gutiérrez… - Frontiers in …, 2022 - frontiersin.org
Metabolic-associated fatty liver disease (MAFLD) is characterized by hepatic steatosis
accompanied by one of three features: overweight or obesity, T2DM, or lean or normal …

[HTML][HTML] miR-34a regulates macrophage-associated inflammation and angiogenesis in alcohol-induced liver injury

Y Wan, E Slevin, S Koyama, CK Huang… - Hepatology …, 2023 - journals.lww.com
Background: Alcohol-associated liver disease (ALD) is a syndrome of progressive
inflammatory liver injury and vascular remodeling associated with long-term heavy intake of …

Pirfenidone use in fibrotic diseases: What do we know so far?

A Torre, FD Martínez‐Sánchez… - Immunity …, 2024 - Wiley Online Library
Background Pirfenidone has demonstrated significant anti‐inflammatory and antifibrotic
effects in both animal models and some clinical trials. Its potential for antifibrotic activity …

[HTML][HTML] Mucoadhesive 3D printed vaginal ovules to treat endometriosis and fibrotic uterine diseases

S Teworte, S Aleandri, JR Weber, M Carone… - European Journal of …, 2023 - Elsevier
Gynaecological health is a neglected field of research that includes conditions such as
endometriosis, uterine fibroids, infertility, viral and bacterial infections, and cancers. There is …

[HTML][HTML] MicroRNA-122 mimic/microRNA-221 inhibitor combination as a novel therapeutic tool against hepatocellular carcinoma

M Hassan, M Elzallat, T Aboushousha… - Non-coding RNA …, 2023 - Elsevier
Abstract Background Therapeutic microRNAs (miRNAs) delivery holds a lot of promise for
treating human malignancies. So, this study was carried out to examine the potential of miR …

Targeting T cell subtypes for NAFLD and NAFLD-related HCC treatment: an opinion

C Zhang, M Yang - Frontiers in Medicine, 2021 - frontiersin.org
The increasing prevalence of non-alcoholic fatty liver disease (NAFLD), as well as its
advanced stage non-alcoholic steatohepatitis (NASH) with the progression of liver …