[HTML][HTML] Sonic Hedgehog Is an Early Oligodendrocyte Marker During Remyelination
Failure of myelin regeneration by oligodendrocytes contributes to progressive decline in
many neurological diseases. Here, using in vitro and in vivo rodent models, functional …
many neurological diseases. Here, using in vitro and in vivo rodent models, functional …
Sonic Hedgehog receptor Patched deficiency in astrocytes enhances glucose metabolism in mice
L Tirou, M Russo, H Faure, G Pellegrino… - Molecular …, 2021 - Elsevier
Objective Astrocytes are glial cells proposed as the main Sonic hedgehog (Shh)-responsive
cells in the adult brain. Their roles in mediating Shh functions are still poorly understood. In …
cells in the adult brain. Their roles in mediating Shh functions are still poorly understood. In …
Smoothened/AMP-activated protein kinase signaling in oligodendroglial cell maturation
A Del Giovane, M Russo, L Tirou, H Faure… - Frontiers in Cellular …, 2022 - frontiersin.org
The regeneration of myelin is known to restore axonal conduction velocity after a
demyelinating event. Remyelination failure in the central nervous system contributes to the …
demyelinating event. Remyelination failure in the central nervous system contributes to the …
Characterization of Sonic Hedgehog transcripts in the adult mouse brain: co-expression with neuronal and oligodendroglial markers
M Russo, G Pellegrino, H Faure, L Tirou… - Brain Structure and …, 2024 - Springer
In the adult mammalian brain, astrocytes are proposed to be the major Sonic Hedgehog
(Shh)-responsive cells. However, the sources of the Shh molecule mediating activation of …
(Shh)-responsive cells. However, the sources of the Shh molecule mediating activation of …
Design, synthesis and biological characterization of a new class of osteogenic (1H)-quinolone derivatives
Smoothened (Smo) is the signal transducer of the Hedgehog (Hh) pathway and its
stimulation is considered a potential powerful tool in regenerative medicine to treat severe …
stimulation is considered a potential powerful tool in regenerative medicine to treat severe …
C9C5 positive mature oligodendrocytes are a source of Sonic Hedgehog in the mouse brain
In the mature rodent brain, Sonic Hedgehog (Shh) signaling regulates stem and progenitor
cell maintenance, neuronal and glial circuitry and brain repair. However, the sources and …
cell maintenance, neuronal and glial circuitry and brain repair. However, the sources and …
Cellular and molecular factors that drive the behavior of oligodendrocyte progenitor cells in physiological conditions and disease
D Lecca, W Baron, AM Butt - Frontiers in cellular neuroscience, 2023 - frontiersin.org
Oligodendrocyte progenitor cells (OPCs) are a subtype of glia giving rise to the myelin
producing cells in the central nervous system. OPCs are not passive actors unavoidably …
producing cells in the central nervous system. OPCs are not passive actors unavoidably …
Etudes moléculaires et pharmacologiques du récepteur Smoothened
L Hoch - 2015 - theses.hal.science
La voie de signalisation Hedgehog (Hh) joue un rôle fondamental au cours du
développement embryonnaire et participe au maintien des niches neurogéniques dans le …
développement embryonnaire et participe au maintien des niches neurogéniques dans le …