Aurones are naturally occurring structural isomerides of flavones that have diverse
bioactivities including antiviral, antibacterial, antifungal, anti-inflammatory, antitumor …

Deemed as poorly represented in nature, aurones have been often overlooked by
researchers compared to other members of the flavonoid superfamily. However, over the …

Abstract Novel pyridine-3-carbonitrile derivatives, denoted as (4a-j), were synthesized using
a convergent synthetic approach that involved a one-pot four-component reaction. This was …

Purpose: Artemisinin (ART) has anti-inflammatory, antimicrobial, antioxidant, anti-amyloid,
and anti-malarial effects, but its application is limited due to its low water solubility and poor …

Cancer is one of the main global health problems. In order to develop novel antitumor
agents, we synthesized 3, 4-dihydropyrimidine-2 (1H)-one (DHPM) and 2, 6-diaryl …

Graphene oxide (GO) and gold/graphene oxide (Au/GO) nanocomposites were fabricated
through a facile chemical route and their application as excellent nanocarriers for curcumin …

Background: The application of plumbagin (PLN), with a wide use in pharmaceutical
science, is limited due to its low water solubility and poor bioavailability. Micelles can …

Due to the challenges in the control, prevention, and eradication of parasitic diseases like
malaria, there is an urgent need to discover new therapeutic agents. Plant‐derived …

A series of aurone compounds with the B ring substituted by different heterocycles has been
synthesized. All synthesized compounds have been tested for antibacterial activity. It has …

Background: Development of resistance against the frontline anti-malarial drugs has created
an alarming situation, which requires intensive drug discovery to develop new, more …