Simple Summary Anoikis is a programmed cell death process resulting from the loss of
interaction between cells and the extracellular matrix. Therefore, it is necessary to overcome …

Abstract The Kruppel-Like Factor family of regulatory proteins, which has 18 members, is
transcription factors. This family contains zinc finger proteins, regulates the activation and …

Background LncRNA-PACERR plays critical role in the polarization of tissue-associated
macrophages (TAMs). In this study, we found the function and molecular mechanism of …

Background Cancer metastasis is determined by the formation of the metastatic niche and
the ability of cancer cells to adapt to microenvironmental stresses. Anoikis resistance is a …

Abstract Background Cancer stem cells (CSCs) play an important role in the development of
pancreatic cancer. We previously showed that the microRNA miR-137 is downregulated in …

Breast cancer is the most common cancer affecting women worldwide. Many genes are
involved in the development of breast cancer, including the Kruppel Like Factor 12 (KLF12) …

Embryonic stem cells (ESCs) can undergo lineage-specific differentiation, giving rise to
different cell types that constitute an organism. Although roles of transcription factors and …

Cutaneous T-cell lymphomas (CTCLs) are a family of primary extranodal lymphomas of
mature CD4+, skin-homing or skin-resident T cells. In a significant fraction of patients with …

High-risk human papillomavirus (hrHPV) infection and integration were considered as
essential onset factors for the development of cervical cancer. However, the mechanism on …

NK cells are innate lymphocytes that play an integral role in tumor rejection and viral
clearance. Unlike their other lymphocyte counterparts, NK cells have the unique ability to …