This paper is the 28th consecutive installment of the annual review of research concerning
the endogenous opioid system, now spanning over a quarter-century of research. It …

During the last 30 years there have been many attempts to develop animal models of
obsessive-compulsive disorder (OCD). Most models have not been studied further following …

Obsessive–compulsive disorder (OCD) is a disabling and common neuropsychiatric
condition of poorly known etiology. Many attempts have been made in the last few years to …

Schizophrenia is a debilitating mental illness that affects approximately 1% of the world's
population. Despite much research in its neurobiology to aid in developing new treatments …

Rationale The use and misuse of prescription opiates in adolescent populations, and in
particular, adolescent female populations, has increased dramatically in the past two …

The dynorphin/κ-opioid receptor (KOR) system has been previously implicated in the
regulation of cognition, but the neural circuitry and molecular mechanisms underlying KOR …

The strength of goal-oriented behaviors is regulated by midbrain dopamine neurons.
Dysfunctions of dopaminergic circuits are observed in drug addiction and obsessive …

Background: Serotonin and dopamine neuronal systems have been implicated in the
modulation of obsessive-compulsive disorder (OCD) symptoms. About 40% of OCD patients …

Obsessive–compulsive disorder (OCD) affects 1%–3% of children worldwide and has a
profound impact on quality of life for patients and families. Although our understanding of the …

Objective The purpose of this literature database search‐based review was to critically
consider and evaluate the findings of literature focusing on efficacy and safety of 5‐HT3 …