Effect of DMARDs on the immunogenicity of vaccines

Y van Sleen, KSM van der Geest… - Nature Reviews …, 2023 - nature.com
Vaccines are important for protecting individuals at increased risk of severe infections,
including patients undergoing DMARD therapy. However, DMARD therapy can also …

Considerations for pharmacologic management of rheumatoid arthritis in the COVID-19 era: a narrative review

R Venkat, ZS Wallace, JA Sparks - Current Rheumatology Reports, 2023 - Springer
Abstract Purpose of Review To review the impact of disease-modifying antirheumatic drugs
(DMARDs) on COVID-19 severity and vaccine immunogenicity and to discuss COVID-19 …

Assessing the risk and costs of COVID-19 in immunocompromised populations in a large United States commercial insurance health plan: the EPOCH-US Study

A Ketkar, V Willey, M Pollack, L Glasser… - … medical research and …, 2023 - Taylor & Francis
Objective To estimate the prevalence of patients with an immunocompromising condition at
risk for COVID-19, estimate COVID-19 prevalence rate (PR) and incidence rate (IR) by …

Immune responses following 3rd and 4th doses of heterologous and homologous COVID-19 vaccines in kidney transplant recipients

T Thomson, M Prendecki, S Gleeson, P Martin… - …, 2022 - thelancet.com
Background Solid organ transplant recipients have attenuated immune responses to SARS-
CoV-2 vaccines. In this study, we report on immune responses to 3rd-(V3) and 4th-(V4) …

American College of Rheumatology Guidance for COVID‐19 vaccination in patients with rheumatic and musculoskeletal diseases: version 5

JR Curtis, SR Johnson, DD Anthony… - Arthritis & …, 2023 - Wiley Online Library
Objective To provide guidance to rheumatology providers on the use of COVID‐19 vaccines
for patients with rheumatic and musculoskeletal diseases (RMDs). Methods A task force was …

Withholding methotrexate after vaccination with ChAdOx1 nCov19 in patients with rheumatoid or psoriatic arthritis in India (MIVAC I and II): results of two, parallel …

TG Skaria, A Sreeprakash, R Umesh… - The Lancet …, 2022 - thelancet.com
Background There is a necessity for an optimal COVID-19 vaccination strategy for
vulnerable population groups, including people with autoimmune inflammatory arthritis on …

Pausing methotrexate prevents impairment of Omicron BA. 1 and BA. 2 neutralisation after COVID-19 booster vaccination

E Habermann, L Gieselmann, P Tober-Lau… - RMD open, 2022 - rmdopen.bmj.com
Objective The level of neutralising capacity against Omicron BA. 1 and BA. 2 after third
COVID-19 vaccination in patients on paused or continuous methotrexate (MTX) therapy is …

[HTML][HTML] The impact of sphingosine-1-phosphate receptor modulators on COVID-19 and SARS-CoV-2 vaccination

D Baker, E Forte, G Pryce, AS Kang, LK James… - Multiple Sclerosis and …, 2023 - Elsevier
Background Sphingosine-one phosphate receptor (S1PR) modulation inhibits S1PR1-
mediated lymphocyte migration, lesion formation and positively-impacts on active multiple …

Methotrexate for inflammatory skin disease in pediatric patients: Consensus treatment guidelines

EC Siegfried, LM Arkin, YE Chiu, AA Hebert… - Pediatric …, 2023 - Wiley Online Library
Methotrexate (MTX) is a readily accessible drug, first used in 1948 and employed for a wide
variety of indications since then. However, despite widespread off‐label use, FDA labeling …

Susceptibility to COVID-19 and immunologic response to vaccination in patients with immune-mediated inflammatory diseases

A Finckh, A Ciurea, CE Raptis… - The Journal of …, 2023 - academic.oup.com
Immune-mediated inflammatory diseases (IMIDs) are a highly heterogeneous group of
diseases that share a common etiology of immune dysregulation, such as rheumatoid …