Glaucoma is a common optic neuropathy with a complex etiology often linked to sensitivity to
intraocular pressure. Though the precise mechanisms that mediate or transduce this …

The function of retinal ganglion cells (RGCs) can be non-invasively assessed in
experimental and genetic models of glaucoma by means of variants of the ERG technique …

A photoreceptor cell line, 661W, derived from a mouse retinal tumor that expresses several
markers of cone photoreceptor cells has been described earlier. However, these cells can …

Purpose.: Involvement of the outer retina is controversial in glaucoma. The aim of this study
was to test, first, whether the outer retina is affected in experimental ocular hypertension …

The protein optineurin coded by OPTN gene is involved in several functions including
regulation of endocytic trafficking, autophagy and signal transduction. Certain missense …

Abstract DBA/2J (D2) mice develop a form of progressive pigmentary glaucoma with
increasing age. We have compared retinal cell populations of D2 mice with those in control …

Purpose To determine whether there are differences in retinal vascular oxygen saturation
measurements, estimated using a hyperspectral fundus camera, between normal eyes and …

Progressive degeneration of retinal ganglion cells (RGCs) will cause a blinding disease.
Most of the study is focusing on the RGCs itself. In this study, we demonstrate a decline of …

Glaucoma is a progressive neurodegenerative disease caused by retinal ganglion cell
(RGC) loss. One important risk factor for glaucoma is elevated intraocular pressure and thus …

Purpose To study alterations in different retinal cell types associated with retinal ganglion
cell (RGC) death after elevation of intraocular pressure (IOP) in rats. Methods IOP was …