Bioresponsive materials

Y Lu, AA Aimetti, R Langer, Z Gu - Nature Reviews Materials, 2016 - nature.com
Abstract 'Smart'bioresponsive materials that are sensitive to biological signals or to
pathological abnormalities, and interact with or are actuated by them, are appealing …

Enzyme-responsive nanomaterials for controlled drug delivery

Q Hu, PS Katti, Z Gu - Nanoscale, 2014 - pubs.rsc.org
Enzymes underpin physiological function and exhibit dysregulation in many disease-
associated microenvironments and aberrant cell processes. Exploiting altered enzyme …

Transformable liquid-metal nanomedicine

Y Lu, Q Hu, Y Lin, DB Pacardo, C Wang, W Sun… - Nature …, 2015 - nature.com
To date, numerous inorganic nanocarriers have been explored for drug delivery systems
(DDSs). However, the clinical application of inorganic formulations has often been hindered …

Bioresponsive drug delivery systems for the treatment of inflammatory diseases

Y Dou, C Li, L Li, J Guo, J Zhang - Journal of Controlled Release, 2020 - Elsevier
Inflammation is intimately related to the pathogenesis of numerous acute and chronic
diseases like cardiovascular disease, inflammatory bowel disease, rheumatoid arthritis, and …

Amino acid derived biopolymers: Recent advances and biomedical applications

SS Gupta, V Mishra, MD Mukherjee, P Saini… - International Journal of …, 2021 - Elsevier
Over the past few years, amino acids (AA) have emerged as promising biomaterials for the
synthesis of functional polymers. Owing to the diversity of functional groups in amino acids …

Amino acid-derived stimuli-responsive polymers and their applications

K Bauri, M Nandi, P De - Polymer Chemistry, 2018 - pubs.rsc.org
Natural biopolymers such as proteins and nucleic acids in living organisms possess an
inherent ability to respond to local environmental stimuli, which motivated researchers to …

Leveraging physiology for precision drug delivery

W Sun, Q Hu, W Ji, G Wright, Z Gu - Physiological reviews, 2017 - journals.physiology.org
Physiological characteristics of diseases bring about both challenges and opportunities for
targeted drug delivery. Various drug delivery platforms have been devised ranging from …

Design principles for bacteria-responsive antimicrobial nanomaterials

JY Quek, E Uroro, N Goswami, K Vasilev - Materials Today Chemistry, 2022 - Elsevier
Despite advancements in biomedical sciences and medicine, bacterial infection remains a
leading cause of death globally. The conventional treatment of bacterial infections through …

Enzyme-triggered, cell penetrating peptide-mediated delivery of anti-tumor agents

H He, L Sun, J Ye, E Liu, S Chen, Q Liang… - Journal of Controlled …, 2016 - Elsevier
Conventional chemotherapy has little or no specificity for cancer cells, normally resulting in
low drug accumulation at the tumor region (inefficacy) and drug-induced severe side effects …

Protein kinase C (PKC) isozymes and cancer

JH Kang - New Journal of Science, 2014 - Wiley Online Library
Protein kinase C (PKC) is a family of phospholipid‐dependent serine/threonine kinases,
which can be further classified into three PKC isozymes subfamilies: conventional or classic …