Protein secretion is an essential process that drives cell growth, movement, and communication. Protein traffic within the secretory pathway occurs via transport …
The adaptor protein (AP) complexes not only form the inner layer of clathrin coats but also have clathrin-independent roles in membrane traffic whose mechanisms are unknown. HIV …
E Pyle, EA Miller, G Zanetti - Nature Structural & Molecular Biology, 2024 - nature.com
Proteins traverse the eukaryotic secretory pathway through membrane trafficking between organelles. The coat protein complex II (COPII) mediates the anterograde transport of newly …
L Wong-Dilworth, G Bregu, S Restel… - bioRxiv, 2023 - biorxiv.org
The endoplasmic reticulum (ER) and the Golgi apparatus are the first sorting stations along the secretory pathway of mammalian cells and have a crucial role in protein quality control …
Y Suda, H Tachikawa, T Suda, K Kurokawa, A Nakano… - Iscience, 2024 - cell.com
Gametogenesis in budding yeast involves a large-scale rearrangement of membrane traffic to allow the de novo formation of a membrane, called the prospore membrane (PSM) …
A Melero, O Muriel-Lopez, M Basante-Bedoya… - bioRxiv, 2024 - biorxiv.org
Endosomes serve as crucial sorting centres that streamline the distribution of cell surface proteins. The early endosome receives traffic from both the plasma membrane (PM) and the …
The endosome is a central sorting station for proteins and lipids. Retrograde protein sorting from the endosome is promoted by conserved SNX-BAR-containing coat complexes …
The Golgi apparatus is a major hub of protein transport, modification and sorting. Secreted and membrane proteins are synthesised in the Endoplasmic Reticulum (ER) and are …