The small GTPase Sar1, control centre of COPII trafficking

SE Van der Verren, G Zanetti - FEBS letters, 2023 - Wiley Online Library
Sar1 is a small GTPase of the ARF family. Upon exchange of GDP for GTP, Sar1 associates
with the endoplasmic reticulum (ER) membrane and recruits COPII components …

Selective inhibition of protein secretion by abrogating receptor–coat interactions during ER export

N Gomez-Navarro, J Maldutyte… - Proceedings of the …, 2022 - National Acad Sciences
Protein secretion is an essential process that drives cell growth, movement, and
communication. Protein traffic within the secretory pathway occurs via transport …

Self-assembly and structure of a clathrin-independent AP-1: Arf1 tubular membrane coat

RM Hooy, Y Iwamoto, DA Tudorica, X Ren… - Science …, 2022 - science.org
The adaptor protein (AP) complexes not only form the inner layer of clathrin coats but also
have clathrin-independent roles in membrane traffic whose mechanisms are unknown. HIV …

Cryo-electron tomography reveals how COPII assembles on cargo-containing membranes

E Pyle, EA Miller, G Zanetti - Nature Structural & Molecular Biology, 2024 - nature.com
Proteins traverse the eukaryotic secretory pathway through membrane trafficking between
organelles. The coat protein complex II (COPII) mediates the anterograde transport of newly …

Nanoscale imaging reveals the mechanisms of ER-to-Golgi transport via a dynamic tubular-vesicular network

L Wong-Dilworth, G Bregu, S Restel… - bioRxiv, 2023 - biorxiv.org
The endoplasmic reticulum (ER) and the Golgi apparatus are the first sorting stations along
the secretory pathway of mammalian cells and have a crucial role in protein quality control …

Remodeling of the secretory pathway is coordinated with de novo membrane formation in budding yeast gametogenesis

Y Suda, H Tachikawa, T Suda, K Kurokawa, A Nakano… - Iscience, 2024 - cell.com
Gametogenesis in budding yeast involves a large-scale rearrangement of membrane traffic
to allow the de novo formation of a membrane, called the prospore membrane (PSM) …

Arp2/3-dependent actin assembly shapes endosomes and promotes intracellular trafficking in fission yeast

A Melero, O Muriel-Lopez, M Basante-Bedoya… - bioRxiv, 2024 - biorxiv.org
Endosomes serve as crucial sorting centres that streamline the distribution of cell surface
proteins. The early endosome receives traffic from both the plasma membrane (PM) and the …

Identification and functional analysis of the endosomal VINE complex in Saccharomyces cerevisiae

SP Shortill - 2023 - open.library.ubc.ca
The endosome is a central sorting station for proteins and lipids. Retrograde protein sorting
from the endosome is promoted by conserved SNX-BAR-containing coat complexes …

Characterising the factors involved in ER-to-Golgi anterograde trafficking

I Yakunin - 2023 - repository.cam.ac.uk
The Golgi apparatus is a major hub of protein transport, modification and sorting. Secreted
and membrane proteins are synthesised in the Endoplasmic Reticulum (ER) and are …