Preventing incubation of drug craving to treat drug relapse: from bench to bedside

X Liu, K Yuan, T Lu, X Lin, W Zheng, Y Xue, J Shi… - Molecular …, 2023 - nature.com
Abstract In 1986, Gawin and Kleber reported a progressive increase in cue-induced drug
craving in individuals with cocaine use disorders during prolonged abstinence. After years of …

Physical exercise rescues cocaine-evoked synaptic deficits in motor cortex

T Cheng, XD Huang, XF Hu, SQ Wang, K Chen… - Molecular …, 2021 - nature.com
Drug exposure impairs cortical plasticity and motor learning, which underlies the reduced
behavioral flexibility in drug addiction. Physical exercise has been used to prevent relapse …

The neurobiological mechanisms underlying the effects of exercise interventions in autistic individuals

G Tu, N Jiang, W Chen, L Liu, M Hu… - Reviews in the …, 2025 - degruyter.com
Autism spectrum disorder is a pervasive and heterogeneous neurodevelopmental condition
characterized by social communication difficulties and rigid, repetitive behaviors. Owing to …

[HTML][HTML] Transcriptional Profile of Exercise-Induced Protection Against Relapse to Cocaine Seeking in a Rat Model

EB Towers, DA Shapiro, JM Abel… - … Psychiatry Global Open …, 2023 - Elsevier
Background Exercise has shown promise as a treatment for cocaine use disorder; however,
the mechanism underlying its efficacy has remained elusive. Methods We used a rat model …

Effects of acute aerobic exercise on sweet taste preference and its brain mechanisms in tobacco addicts

H Liu, Y Han, W Liang, L Zhou, Y Zhang, P Sun, H Fan… - 2024 - researchsquare.com
Aerobic exercise can improve cravings for smoking and inhibition control in tobacco-
dependent individuals; however, its effect on their sweet taste preferences remains unclear …