In nature, chiral natural products are usually produced in optically pure form—however,
occasionally both enantiomers are formed. These enantiomeric natural products can arise …

The Knoevenagel condensation reaction is a prominent organic reaction commonly being
utilized in the total synthesis of natural and biologically potent products as a vital and …

A highly efficient and stereoselective synthesis of coumarin-, 1, 3-cyclohexanedione-, and 1,
4-naphthoquinone-fused 2, 8-dioxabicyclo [3.3. 1] nonanes is described. This was achieved …

The first modular and flexible synthesis of core‐chiral bispidines was achieved by using an
“inside‐out” strategy. The key intermediate, a NBoc‐activated bispidine lactam, was …

An increasing number of synthetic organic chemists are embracing the philosophy of
efficiency. Herein we highlight multi-bond forming processes, which form two or more new …

Bisquinolizidine alkaloids are characterized by a chiral bispidine core (3, 7‐diazabicyclo
[3.3. 1] nonane) to which combinations of an α, N‐fused 2‐pyridone, an endo‐or exo‐α, N …

Both enantiomers of sparteine have suffered from pricing and supply chain variability, which
has inspired efforts toward efficient chemical synthesis. Here, we build upon our reported …

The reactions of a series of strained bicyclic and tricyclic one-carbon bridged lactams with
organometallic reagents have been investigated. These amides permit isolation of a number …

Abstract The well‐established Hoppe–Beak chemistry, which involves enantioselective
generation of organolithium compounds in the presence of (−)‐sparteine, was revisited and …

This is a review of papers published in the year 2008 that focus on the synthesis, reactivity,
or properties of compounds containing a carbon-transition metal double or triple bond.