Impact of magnetic resonance imaging targeting on pathologic upgrading and downgrading at prostatectomy: a systematic review and meta-analysis

IC Weinstein, X Wu, A Hill, D Brennan… - European Urology …, 2023 - Elsevier
Context The evidence supporting multiparametric magnetic resonance imaging (MRI)
targeting for biopsy is nearly exclusively based on biopsy pathologic outcomes. This is …

Factors associated with variability in the performance of a proprietary sepsis prediction model across 9 networked hospitals in the US

PG Lyons, MR Hofford, CY Sean… - JAMA internal …, 2023 - jamanetwork.com
Methods| This cohort study enrolled consecutive adult patients presenting to 1 of 9 hospitals
in a large network (BJC HealthCare) between January 1, 2020, and June 30, 2022 …

Use of active surveillance vs definitive treatment among men with low-and favorable intermediate–risk prostate cancer in the US between 2010 and 2018

BAH Al Awamlh, DA Barocas, A Zhu… - JAMA Internal …, 2023 - jamanetwork.com
Methods| The cross-sectional study was approved by Vanderbilt University Medical Center's
Institutional Review Board. The deidentified data were analyzed from May 15 to September …

PI-RADS version 2.0 versus version 2.1: comparison of prostate cancer gleason grade upgrade and downgrade rates from MRI-targeted biopsy to radical …

EC Yilmaz, Y Lin, MJ Belue… - American Journal of …, 2024 - Am Roentgen Ray Soc
BACKGROUND. Precise risk stratification through MRI/ultrasound (US) fusion-guided
targeted biopsy (TBx) can guide optimal prostate cancer (PCa) management. OBJECTIVE …

Old men with prostate cancer have higher risk of Gleason score upgrading and pathological upstaging after initial diagnosis: a systematic review and meta-analysis

X Wang, Y Zhang, Z Ji, P Yang, Y Tian - World Journal of Surgical …, 2021 - Springer
Background To evaluate the predictive performance of age for the risk of Gleason score
change and pathologic upstaging. Evidence acquisition Ovid MEDLINE, Ovid Embase, and …

Intensity of observation with active surveillance or watchful waiting in men with prostate cancer in the United States

B Al Hussein Al Awamlh, X Wu, DA Barocas… - Prostate cancer and …, 2023 - nature.com
Background Population-based studies assessing various active surveillance (AS) protocols
for prostate cancer, to date, have inferred AS participation by the lack of definitive treatment …

Biomarker vs MRI-Enhanced Strategies for Prostate Cancer Screening: The STHLM3-MRI Randomized Clinical Trial

L Björnebo, A Discacciati, U Falagario… - JAMA Network …, 2024 - jamanetwork.com
Importance Prostate cancer guidelines often recommend obtaining magnetic resonance
imaging (MRI) before a biopsy, yet MRI access is limited. To date, no randomized clinical …

Can 68Ga-PSMA-11 PET/CT predict pathological upgrading of prostate cancer from MRI-targeted biopsy to radical prostatectomy?

H Yin, M Chen, X Qiu, L Qiu, J Gao, D Li, Y Fu… - European Journal of …, 2021 - Springer
Purpose Prostate-specific membrane antigen (PSMA) positron emission tomography (PSMA-
PET) is an ideal tool for staging and restaging of prostate cancer (PCa). This study was …

Prostate cancer grade downgrading at time of prostatectomy provides risk‐stratification insight into future tumor behavior after prostatectomy

S Wang, J Ryan Russell, M Drescher, A Park… - The …, 2022 - Wiley Online Library
Abstract Background Prostate biopsy (Bx) sampling‐based diagnosis of prostate cancer
(PCa) has well‐described inaccuracy when compared against whole gland analysis upon …

Combined systematic and MRI-US fusion prostate biopsy has the highest grading accuracy when compared to final pathology

I Andras, ED Cata, A Serban, P Kadula, T Telecan… - Medicina, 2021 - mdpi.com
Background and objectives: Systematic prostate biopsy (SB) has a low Gleason group (GG)
accuracy when compared to final pathology. This may negatively impact the inclusion of …