Polymeric nanoparticles for delivery of natural bioactive agents: recent advances and challenges

M Elmowafy, K Shalaby, MH Elkomy, OA Alsaidan… - Polymers, 2023 - mdpi.com
In the last few decades, several natural bioactive agents have been widely utilized in the
treatment and prevention of many diseases owing to their unique and versatile therapeutic …

Novel nanomedicines to overcome cancer multidrug resistance

Z Su, S Dong, SC Zhao, K Liu, Y Tan, X Jiang… - Drug Resistance …, 2021 - Elsevier
Chemotherapy remains a powerful tool to eliminate malignant cells. However, the efficacy of
chemotherapy is compromised by the frequent emergence of intrinsic and acquired …

Surface modification of lipid-based nanoparticles

Y Xu, T Fourniols, Y Labrak, V Préat, A Beloqui… - ACS …, 2022 - ACS Publications
There is a growing interest in the development of lipid-based nanocarriers for multiple
purposes, including the recent increase of these nanocarriers as vaccine components …

Synthetic molecular motor activates drug delivery from polymersomes

A Guinart, M Korpidou, D Doellerer… - Proceedings of the …, 2023 - National Acad Sciences
The design of stimuli-responsive systems in nanomedicine arises from the challenges
associated with the unsolved needs of current molecular drug delivery. Here, we present a …

Nanocarriers for skin applications: where do we stand?

N Tiwari, ER Osorio‐Blanco, A Sonzogni… - Angewandte Chemie …, 2022 - Wiley Online Library
Skin penetration of active molecules for treatment of diverse diseases is a major field of
research owing to the advantages associated with the skin like easy accessibility, reduced …

Novel drug delivery systems for loading of natural plant extracts and their biomedical applications

HS Rahman, HH Othman, NI Hammadi… - International journal …, 2020 - Taylor & Francis
Many types of research have distinctly addressed the efficacy of natural plant metabolites
used for human consumption both in cell culture and preclinical animal model systems …

[HTML][HTML] Polymer bioconjugates: Modern design concepts toward precision hybrid materials

C Chen, DYW Ng, T Weil - Progress in Polymer Science, 2020 - Elsevier
The conjugation of synthetic polymers with various biomolecules provides an easy access to
biohybrid materials which combine advantages from both the synthetic world and Nature …

Delivery of cancer therapies by synthetic and bio-inspired nanovectors

T Briolay, T Petithomme, M Fouet, N Nguyen-Pham… - Molecular cancer, 2021 - Springer
Background As a complement to the clinical development of new anticancer molecules,
innovations in therapeutic vectorization aim at solving issues related to tumor specificity and …

Emerging role of nanoclays in cancer research, diagnosis, and therapy

D Peixoto, I Pereira, M Pereira-Silva, F Veiga… - Coordination Chemistry …, 2021 - Elsevier
Cancer remains one of the deadliest diseases, and its effective diagnosis and treatment
remains challenging; therefore, progress in earlier detection and improved therapeutics are …

Mechanistic understanding from molecular dynamics simulation in pharmaceutical research 1: drug delivery

A Bunker, T Róg - Frontiers in Molecular Biosciences, 2020 - frontiersin.org
In this review, we outline the growing role that molecular dynamics simulation is able to play
as a design tool in drug delivery. We cover both the pharmaceutical and computational …