Voltage‐gated calcium channels are essential players in many physiological processes in
excitable cells. There are three main subdivisions of calcium channel, defined by the pore …

The L-type Cav1. 2 calcium channel is present throughout the animal kingdom and is
essential for some aspects of CNS function, cardiac and smooth muscle contractility …

The voltage-gated calcium channel α2δ and β subunits are traditionally considered to be
auxiliary subunits that enhance channel trafficking, increase the expression of functional …

Voltage-gated calcium channels consist of the main pore-forming α1 subunit, together,
except in the case of the T-type channels, with β and α2δ and sometimes γ subunits, which …

Psychiatric disorders are mental, behavioral or emotional disorders. These conditions are
prevalent, one in four adults suffer from any type of psychiatric disorders world-wide. It has …

Voltage-gated calcium (Ca V) channels are associated with β and α 2 δ auxiliary subunits.
This review will concentrate on the function of the α 2 δ protein family, which has four …

Voltage‐gated calcium channels (VGCCs) represent the sole mechanism to convert
membrane depolarization into cellular functions like secretion, contraction, or gene …

Action potential-evoked neurotransmitter release is impaired in knock-out neurons lacking
synaptic cell-adhesion molecules α-neurexins (αNrxns), the extracellularly longer variants of …

Abstract α 2 δ proteins are membrane-anchored extracellular glycoproteins which are
abundantly expressed in the brain and the peripheral nervous system. They serve as …

Excitation-evoked calcium influx across cellular membranes is strictly controlled by voltage-
gated calcium channels (CaV), which possess four distinct voltage-sensing domains (VSDs) …