NK cell recognition

LL Lanier - Annu. Rev. Immunol., 2005 - annualreviews.org
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Structure and regulation of Src family kinases

TJ Boggon, MJ Eck - Oncogene, 2004 - nature.com
Src family kinases are prototypical modular signaling proteins. Their conserved domain
organization includes a myristoylated N-terminal segment followed by SH3, SH2, and …

[HTML][HTML] SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

MJ Kiel, ÖH Yilmaz, T Iwashita, OH Yilmaz, C Terhorst… - cell, 2005 - cell.com
To improve our ability to identify hematopoietic stem cells (HSCs) and their localization in
vivo, we compared the gene expression profiles of highly purified HSCs and non-self …

Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort study

L Beaugerie, N Brousse, AM Bouvier, JF Colombel… - The Lancet, 2009 - thelancet.com
Background Reports of an increased risk of lymphoproliferative disorders in patients
receiving thiopurines for inflammatory bowel disease are controversial. We assessed this …

Sjögren's syndrome: old and new therapeutic targets

CP Mavragani, HM Moutsopoulos - Journal of autoimmunity, 2020 - Elsevier
Sjögren's syndrome (SS) is a prototype autoimmune disease characterized by oral and
ocular mucosal dryness following chronic inflammation of salivary and lachrymal glands …

T follicular helper cells in germinal center B cell selection and lymphomagenesis

MA Mintz, JG Cyster - Immunological reviews, 2020 - Wiley Online Library
Germinal centers (GCs) are confined anatomic regions where rapidly proliferating B cells
undergo somatic mutation and selection and eventual differentiation into memory B cells or …

Follicular B helper T cells in antibody responses and autoimmunity

CG Vinuesa, SG Tangye, B Moser… - Nature reviews …, 2005 - nature.com
T-cell help for B cells is essential for high-affinity antibody responses and B-cell memory.
Recently, the identity of a discrete follicular population of T cells that has a crucial role in this …

SLAMF3 and SLAMF4 are immune checkpoints that constrain macrophage phagocytosis of hematopoietic tumors

D Li, W Xiong, Y Wang, J Feng, Y He, J Du… - Science …, 2022 - science.org
The interaction of SIRPα with CD47 represents a major mechanism for preventing
macrophage phagocytosis. However, CD47-independent mechanisms are poorly defined …

[HTML][HTML] Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development

K Griewank, C Borowski, S Rietdijk, N Wang, A Julien… - Immunity, 2007 - cell.com
Commitment to the T and natural killer T (NKT) cell lineages is determined during αβ T cell
receptor (TCR)-mediated interactions of common precursors with ligand-expressing cells in …

New insights into the molecular mechanism of interleukin-10-mediated immunosuppression

G Grütz - Journal of leukocyte biology, 2005 - academic.oup.com
Abstract Interleukin-10 (IL-10) is an important immunomodulatory cytokine, which has
attracted much attention because of its anti-inflammatory properties. It reduces antigen …