Guidelines and quality criteria for artificial intelligence-based prediction models in healthcare: a scoping review

AAH de Hond, AM Leeuwenberg, L Hooft… - NPJ digital …, 2022 - nature.com
While the opportunities of ML and AI in healthcare are promising, the growth of complex data-
driven prediction models requires careful quality and applicability assessment before they …

Risk of bias in studies on prediction models developed using supervised machine learning techniques: systematic review

CLA Navarro, JAA Damen, T Takada, SWJ Nijman… - bmj, 2021 - bmj.com
Objective To assess the methodological quality of studies on prediction models developed
using machine learning techniques across all medical specialties. Design Systematic …

Metabolomic profiles predict individual multidisease outcomes

T Buergel, J Steinfeldt, G Ruyoga, M Pietzner… - Nature medicine, 2022 - nature.com
Risk stratification is critical for the early identification of high-risk individuals and disease
prevention. Here we explored the potential of nuclear magnetic resonance (NMR) …

Prevalence and risk factors for mental health problems in university undergraduate students: A systematic review with meta-analysis

E Sheldon, M Simmonds-Buckley, C Bone… - Journal of affective …, 2021 - Elsevier
Background: Effective targeting of services requires that we establish which undergraduates
are at increased risk of mental health problems at university. We aimed to conduct a …

Calculating the sample size required for developing a clinical prediction model

RD Riley, J Ensor, KIE Snell, FE Harrell, GP Martin… - Bmj, 2020 - bmj.com
Clinical prediction models aim to predict outcomes in individuals, to inform diagnosis or
prognosis in healthcare. Hundreds of prediction models are published in the medical …

PROBAST: a tool to assess the risk of bias and applicability of prediction model studies

RF Wolff, KGM Moons, RD Riley, PF Whiting… - Annals of internal …, 2019 - acpjournals.org
Clinical prediction models combine multiple predictors to estimate risk for the presence of a
particular condition (diagnostic models) or the occurrence of a certain event in the future …

Minimum sample size for external validation of a clinical prediction model with a binary outcome

RD Riley, TPA Debray, GS Collins, L Archer… - Statistics in …, 2021 - Wiley Online Library
In prediction model research, external validation is needed to examine an existing model's
performance using data independent to that for model development. Current external …

PROBAST: a tool to assess risk of bias and applicability of prediction model studies: explanation and elaboration

KGM Moons, RF Wolff, RD Riley, PF Whiting… - Annals of internal …, 2019 - acpjournals.org
Prediction models in health care use predictors to estimate for an individual the probability
that a condition or disease is already present (diagnostic model) or will occur in the future …

Minimum sample size for developing a multivariable prediction model: PART II‐binary and time‐to‐event outcomes

RD Riley, KIE Snell, J Ensor, DL Burke… - Statistics in …, 2019 - Wiley Online Library
When designing a study to develop a new prediction model with binary or time‐to‐event
outcomes, researchers should ensure their sample size is adequate in terms of the number …

Predictive accuracy of a polygenic risk score–enhanced prediction model vs a clinical risk score for coronary artery disease

J Elliott, B Bodinier, TA Bond, M Chadeau-Hyam… - Jama, 2020 - jamanetwork.com
Importance The incremental value of polygenic risk scores in addition to well-established
risk prediction models for coronary artery disease (CAD) is uncertain. Objective To examine …