Platelet activation plays a pivotal role in the development and progression of
atherosclerosis, which often leads to potentially fatal ischemic events at later stages of the …

Objective Aspirin resistance (AR) and clopidogrel resistance (CR) are terms used to
describe a reduction in the medication's efficacy in inhibiting platelet aggregation despite …

Given the high morbidity and mortality of cardiovascular diseases (CVDs), novel biomarkers
for platelet reactivity are urgently needed. Ischemic events in CVDs are causally linked to …

Significance: Cardiovascular disease (CVD) remains the major cause of morbidity and
mortality worldwide. Accumulating evidence indicates that atherosclerosis and its sequelae …

1.1. Purpose The European Society for Vascular Surgery (ESVS) has developed a series of
clinical practice guidelines for clinicians caring for patients with vascular diseases. This is …

Over the past four decades, percutaneous coronary intervention (PCI) safety and efficacy
have significantly improved, particularly with the advent of the drug-eluting stent (DES). First …

Essentials• The diagnosis of mild platelet function disorders (PFDs) is challenging.•
Validation of flow cytometric testing in patients with suspected PFDs is required.• Flow …

Objectives Carotid stenosis patients are at risk of vascular events despite antiplatelet
therapy. Data on prescribed antiplatelet regimens have not been comprehensively collated …

Reticulated platelets (RP) are young, functionally active platelet forms which are detected by
RNA staining. Their content in the circulation reflects the intensity of bone marrow …

The key role played by platelets in the atherosclerosis physiopathology, especially in the
acute setting, is ascertained: they are the main actors during thrombus formation and, thus …