Glioblastoma (GBM) is a primary tumor of the brain defined by its uniform lethality and
resistance to conventional therapies. There have been considerable efforts to untangle the …

Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …

In the current phase of medical progress, practical neuro-oncology faces critical challenges.
These include the quest for and development of innovative methodological approaches, as …

Cholesterol is a structural component of cell membranes. How rapidly growing tumor cells
maintain membrane cholesterol homeostasis is poorly understood. Here, we found that …

Abstract Background N6-methyladenosine (m6A) modification is the most abundant
reversible methylation modification in eukaryotes, and it is reportedly closely associated with …

Photodynamic therapy (PDT)‐mediated cancer immunotherapy is attenuated due to the
dysfunction of T cells in immunosuppressive tumor microenvironment (TME). Cholesterol …

Glioblastoma (GBM) is a highly aggressive and lethal brain tumor with limited treatment
options, such as the chemotherapeutic agent, temozolomide (TMZ). However, many GBM …

Introduction Abnormal lipid metabolism, one of the hallmarks in cancer, has gradually
emerged as a novel target for cancer treatment. As organelles that store and release excess …

Brain tumors account for less than 2% of all malignancies. However, they are associated
with the highest morbidity and mortality rates among all solid tumors. The most common …

Background/Objectives: Despite current treatments extending the lifespan of Glioblastoma
(GBM) patients, the average survival time is around 15–18 months, underscoring the fatality …