The major spliceosome mediates pre-mRNA splicing by recognizing the highly conserved
sequences at the 5′ and 3′ splice sites and the branch point. More than 150 proteins …

Mutations in transition zone genes change the composition of the ciliary proteome. We
isolated new mutations in RPGRIP1L (denotated as RPG1 in algae) that affect the …

Genome-wide analysis of transcriptome data in Chlamydomonas reinhardtii shows periodic
patterns in gene expression levels when cultures are grown under alternating light and dark …

Chlamydomonas has become a premier model organism thanks to the ease with which
gene function can be analyzed experimentally. With the advent of genome and …

FRA10AC1, the causative gene for the manifestation of the FRA10A fragile site, encodes a
well-conserved nuclear protein characterized as a non-core spliceosomal component. Pre …

Motile cilia are complex organelles comprised of> 800 structural proteins. Variants in 58 of
these genes cause primary ciliary dyskinesia (PCD) in humans. We used a second-site non …

Primary cilia are microtubule-based cell organelles that are required for the communication
between cells in a tissue and the regulation of intracellular signalling pathways. They are …

Το γονίδιο FRA10AC1 εντοπίζεται στην σπάνια εύθραυστη χρωμοσωματική θέση FRA10A, η
οποία επάγεται απουσία φυλλικού οξέος στο θρεπτικό μέσο καλλιέργειας των κυττάρων, στην …