Mutant-Huntingtin Molecular Pathways Elucidate New Targets for Drug Repurposing
VS Makeeva, NS Dyrkheeva, OI Lavrik… - International Journal of …, 2023 - mdpi.com
The spectrum of neurodegenerative diseases known today is quite extensive. The
complexities of their research and treatment lie not only in their diversity. Even many years of …
complexities of their research and treatment lie not only in their diversity. Even many years of …
Selection of Multi-Drug Targets against Drug-Resistant Mycobacterium tuberculosis XDR1219 Using the Hyperbolic Mapping of the Protein Interaction Network
NA Zahra, AC Vagiona, R Uddin… - International Journal of …, 2023 - mdpi.com
Tuberculosis remains the leading cause of death from a single pathogen. On the other hand,
antimicrobial resistance (AMR) makes it increasingly difficult to deal with this disease. We …
antimicrobial resistance (AMR) makes it increasingly difficult to deal with this disease. We …
Intranuclear inclusions of polyQ-expanded ATXN1 sequester RNA molecules
I Gkekas, AC Vagiona, N Pechlivanis… - Frontiers in Molecular …, 2023 - frontiersin.org
Spinocerebellar ataxia type 1 (SCA1) is an autosomal dominant neurodegenerative disease
caused by a trinucleotide (CAG) repeat expansion in the ATXN1 gene. It is characterized by …
caused by a trinucleotide (CAG) repeat expansion in the ATXN1 gene. It is characterized by …
Molecular research on Huntington's disease
LM Valor - International Journal of Molecular Sciences, 2023 - mdpi.com
Huntington's disease (HD) is a devastating neurodegenerative disorder caused by an
aberrant expansion of CAG triplets in the HTT (Huntingtin) gene. This mutation leads to the …
aberrant expansion of CAG triplets in the HTT (Huntingtin) gene. This mutation leads to the …
Two cGMP-dependent protein kinases have opposing effects on molt-inhibiting hormone regulation of Y-organ ecdysteroidogenesis
TB Head, JL Pérez-Moreno, T Ventura… - Journal of …, 2025 - journals.biologists.com
Decapod crustaceans regulate molting through steroid molting hormones, ecdysteroids,
synthesized by the molting gland (Y-organ, YO). Molt-inhibiting hormone (MIH), a …
synthesized by the molting gland (Y-organ, YO). Molt-inhibiting hormone (MIH), a …
Genetic analysis and prenatal diagnosis of short-rib thoracic dysplasia 3 with or without polydactyly caused by compound heterozygous variants of DYNC2H1 gene in …
Y Fang, S Li, D Yu - Frontiers in Genetics, 2023 - frontiersin.org
Background: To describe the genetic variation of dynein cytoplasmic 2 heavy chain 1
(DYNC2H1) gene in four Chinese families affected with short-rib thoracic dysplasia 3 with or …
(DYNC2H1) gene in four Chinese families affected with short-rib thoracic dysplasia 3 with or …
[PDF][PDF] Prediction of the Function of Protein Interactions in Post-Translational Modifications
AC Vagiona - cbdm.uni-mainz.de
Prediction of the Function of Protein Interactions in Post-Translational Modifications Page 1
Prediction of the Function of Protein Interactions in Post-Translational Modifications Mainz …
Prediction of the Function of Protein Interactions in Post-Translational Modifications Mainz …