The evolving role of CD4 cell counts in HIV care

N Ford, G Meintjes, M Vitoria, G Greene… - Current Opinion in HIV …, 2017 - journals.lww.com
The evolving role of CD4 cell counts in HIV care : Current Opinion in HIV and AIDS The
evolving role of CD4 cell counts in HIV care : Current Opinion in HIV and AIDS Log in or …

Aiming for protective T-cell responses: a focus on the first generation conserved-region HIVconsv vaccines in preventive and therapeutic clinical trials

T Hanke - Expert Review of Vaccines, 2019 - Taylor & Francis
Introduction: Despite life-saving antiretroviral drugs, an effective HIV-1 vaccine is the best
solution and likely a necessary component of any strategy for halting the AIDS epidemic …

British HIV Association guidelines for the treatment of HIV-1-positive adults with antiretroviral therapy 2015

D Churchill, L Waters, N Ahmed, B Angus… - HIV …, 2016 - discovery.ucl.ac.uk
The overall purpose of these guidelines is to provide guidance on best clinical practice in
the treatment and management of adults with HIV infection on antiretroviral therapy (ART) …

[HTML][HTML] Untangling the Gordian knot of HIV, stress, and cognitive impairment

AN Valdez, LH Rubin, GN Neigh - Neurobiology of stress, 2016 - Elsevier
As individuals live longer with HIV, this “graying of the HIV epidemic” has introduced a new
set of challenges including a growing number of age and inflammation-related diseases …

Virological blips and predictors of post treatment viral control after stopping ART started in primary HIV infection

S Fidler, AD Olson, HC Bucher, J Fox… - JAIDS Journal of …, 2017 - journals.lww.com
Background: Few individuals commencing antiretroviral therapy (ART) in primary HIV
infection (PHI) maintain undetectable viremia after treatment cessation. Associated factors …

Might dolutegravir be part of a functional cure for HIV?

MA Wainberg, YS Han… - Canadian journal of …, 2016 - cdnsciencepub.com
Antiretroviral therapy (ART) has greatly decreased HIV-related morbidity and mortality.
However, HIV can establish viral reservoirs that evade both the immune system and ART …

The multifaceted contributions of chromatin to HIV-1 integration, transcription, and latency

E De Crignis, T Mahmoudi - international review of cell and molecular …, 2017 - Elsevier
The capacity of the human immunodeficiency virus (HIV-1) to establish latent infections
constitutes a major barrier to the development of a cure for HIV-1. In latent infection …

[HTML][HTML] Update and new directions in therapeutics for neurological complications of HIV infections

R Ellis, SL Letendre - Neurotherapeutics, 2016 - Elsevier
The pace of therapeutic developments in HIV presents unique challenges to the neurologist
caring for patients. Combination antiretroviral therapy (cART) is remarkably effective in …

HIV-1 immunogen: an overview of almost 30 years of clinical testing of a candidate therapeutic vaccine

GM Graziani, JB Angel - Expert opinion on biological therapy, 2016 - Taylor & Francis
Introduction: Although current antiretroviral therapy (ART) has transformed HIV infection into
a chronic, manageable disease, ART does not cure HIV infection. Furthermore, the majority …

Hematopoietic stem and immune cells in chronic HIV infection

J Zhang, C Crumpacker - Stem Cells International, 2015 - Wiley Online Library
Hematopoietic stem cell (HSC) belongs to multipotent adult somatic stem cells. A single
HSC can reconstitute the entire blood system via self‐renewal, differentiation into all …