Epstein–Barr virus: more than 50 years old and still providing surprises

LS Young, LF Yap, PG Murray - Nature reviews cancer, 2016 - nature.com
It is more than 50 years since the Epstein–Barr virus (EBV), the first human tumour virus, was
discovered. EBV has subsequently been found to be associated with a diverse range of …

The role of Epstein–Barr virus in nasopharyngeal carcinoma

ZY Su, PY Siak, CO Leong, SC Cheah - Frontiers in Microbiology, 2023 - frontiersin.org
Nasopharyngeal carcinoma (NPC) is a metastasis-prone malignancy closely associated
with the Epstein–Barr virus (EBV). Despite ubiquitous infection of EBV worldwide, NPC …

EBV miRNAs BART11 and BART17-3p promote immune escape through the enhancer-mediated transcription of PD-L1

J Wang, J Ge, Y Wang, F Xiong, J Guo, X Jiang… - Nature …, 2022 - nature.com
Epstein-Barr virus (EBV) is reportedly the first identified human tumor virus, and is closely
related to the occurrence and development of nasopharyngeal carcinoma (NPC), gastric …

The role of Epstein–Barr virus in epithelial malignancies

SW Tsao, CM Tsang, KF To, KW Lo - The Journal of pathology, 2015 - Wiley Online Library
The close association of Epstein–Barr virus (EBV) infection with non‐keratinizing
nasopharyngeal carcinomas and a subset of gastric carcinomas suggests that EBV infection …

Update on Epstein-Barr virus and gastric cancer

A Shinozaki-Ushiku, A Kunita… - … journal of oncology, 2015 - spandidos-publications.com
Epstein-Barr virus-associated gastric carcinoma (EBVaGC) is a distinct subtype that
accounts for nearly 10% of gastric carcinomas. EBVaGC is defined by monoclonal …

EBV-positive gastric cancer: current knowledge and future perspectives

K Sun, K Jia, H Lv, SQ Wang, Y Wu, H Lei… - Frontiers in …, 2020 - frontiersin.org
Gastric cancer is the fifth most common malignant tumor and second leading cause of
cancer-related deaths worldwide. With the improved understanding of gastric cancer, a …

Chemotherapy and chemo-resistance in nasopharyngeal carcinoma

S Guan, J Wei, L Huang, L Wu - European Journal of Medicinal Chemistry, 2020 - Elsevier
Nasopharyngeal carcinoma (NPC) is closely associated with Epstein-Barr virus (EBV) and
occurs frequently in the south of China and Southeast Asian countries. Concurrent chemo …

[HTML][HTML] Translational genomics of nasopharyngeal cancer

CM Tsang, VWY Lui, JP Bruce, TJ Pugh… - Seminars in cancer biology, 2020 - Elsevier
Nasopharyngeal carcinoma (NPC), also named the Cantonese cancer, is a unique cancer
with strong etiological association with infection of the Epstein-Barr virus (EBV). With …

Epstein–Barr virus-encoded microRNA BART1 induces tumour metastasis by regulating PTEN-dependent pathways in nasopharyngeal carcinoma

L Cai, Y Ye, Q Jiang, Y Chen, X Lyu, J Li… - Nature …, 2015 - nature.com
Abstract Epstein–Barr virus (EBV), aetiologically linked to nasopharyngeal carcinoma
(NPC), is the first human virus found to encode many miRNAs. However, how these viral …

EBV-miR-BART7-3p promotes the EMT and metastasis of nasopharyngeal carcinoma cells by suppressing the tumor suppressor PTEN

LM Cai, XM Lyu, WR Luo, XF Cui, YF Ye, CC Yuan… - Oncogene, 2015 - nature.com
The epithelial-mesenchymal transition (EMT) is crucial to cancer progression and
metastasis. Although multiple cellular miRNAs have been identified to regulate the EMT and …