Chemical tools have accelerated progress in glycoscience, reducing experimental barriers to studying protein glycosylation, the most widespread and complex form of posttranslational …
Mesenchymal stem cells (MSCs) are multipotent cells with a substantial potential in human regenerative medicine due to their ability to migrate to sites of injury, capability to suppress …
Glycosylation is one of the most common protein modifications and is essential for cells. This modification is exceptionally complex because glycans are highly diverse and can be …
Generation of induced pluripotent stem cells (iPSCs) is a process whose mechanistic underpinnings are only beginning to emerge. Here, we applied in-depth quantitative …
The plasma membrane proteome is a rich resource of functionally important and therapeutically relevant protein targets. Distinguished by high hydrophobicity, heavy …
Z Chen, J Huang, L Li - TrAC Trends in Analytical Chemistry, 2019 - Elsevier
Protein glycosylation plays a key role in various biological processes and disease-related pathological progression. Mass spectrometry (MS)-based glycoproteomics is a powerful …
O Vit, J Petrak - Journal of Proteomics, 2017 - Elsevier
Integral membrane proteins (IMPs) are coded by 20–30% of human genes and execute important functions–transmembrane transport, signal transduction, cell-cell communication …
S Bhattacharya, PW Burridge, EM Kropp… - Journal of …, 2014 - pmc.ncbi.nlm.nih.gov
There is an urgent need to develop approaches for repairing the damaged heart, discovering new therapeutic drugs that do not have toxic effects on the heart, and improving …
The term 'exoproteome'describes the protein content that can be found in the extracellular proximity of a given biological system. These proteins arise from cellular secretion, other …