Hybrid exosomes, exosome-like nanovesicles and engineered exosomes for therapeutic applications

J Mondal, S Pillarisetti, V Junnuthula, M Saha… - Journal of Controlled …, 2023 - Elsevier
Exosomes are endosome-derived nanovesicles involved in cellular communication. They
are natural nanocarriers secreted by various cells, making them suitable candidates for …

Exosomes, a new star for targeted delivery

H Chen, L Wang, X Zeng, H Schwarz… - Frontiers in cell and …, 2021 - frontiersin.org
Exosomes are cell-secreted nanoparticles (generally with a size of 30–150 nm) bearing
numerous biological molecules including nucleic acids, proteins and lipids, which are …

The biology, function, and biomedical applications of exosomes

R Kalluri, VS LeBleu - Science, 2020 - science.org
BACKGROUND All cells, prokaryotes and eukaryotes, release extracellular vesicles (EVs)
as part of their normal physiology and during acquired abnormalities. EVs can be broadly …

Advances in exosome-based drug delivery and tumor targeting: from tissue distribution to intracellular fate

J Shao, J Zaro, Y Shen - International journal of nanomedicine, 2020 - Taylor & Francis
Exosomes or small extracellular vesicles are considered a new generation of bioinspired-
nanoscale drug delivery system (DDS). Endogenous exosomes function as signalosomes …

Ti3C2 MXenes nanosheets catalyzed highly efficient electrogenerated chemiluminescence biosensor for the detection of exosomes

H Zhang, Z Wang, Q Zhang, F Wang, Y Liu - Biosensors and Bioelectronics, 2019 - Elsevier
Exosomes have been reported to play an important role in the anti-tumor immune response,
tumor diagnosis and other processes, and are promising biomarkers for early cancer …

In Situ Formation of Gold Nanoparticles Decorated Ti3C2 MXenes Nanoprobe for Highly Sensitive Electrogenerated Chemiluminescence Detection of Exosomes …

H Zhang, Z Wang, F Wang, Y Zhang, H Wang… - Analytical …, 2020 - ACS Publications
In this work, an ultrasensitive electrogenerated chemiluminescence (ECL) biosensor for
exosomes and their surface proteins was developed by the in situ formation of gold …

Bone marrow-derived mesenchymal stem cells-derived exosomes promote survival of retinal ganglion cells through miRNA-dependent mechanisms

B Mead, S Tomarev - Stem cells translational medicine, 2017 - academic.oup.com
The loss of retinal ganglion cells (RGC) and their axons is one of the leading causes of
blindness and includes traumatic (optic neuropathy) and degenerative (glaucoma) eye …

Mesenchymal stem cell exosomes: a two-edged sword in cancer therapy

F Vakhshiteh, F Atyabi, SN Ostad - International journal of …, 2019 - Taylor & Francis
Mesenchymal stem cells (MSCs) are multipotent stromal cells present in various adult
tissues. Several studies suggest that MSCs secrete exosomes that perform as mediators in …

Exosomes as drug carriers in anti-cancer therapy

L Chen, L Wang, L Zhu, Z Xu, Y Liu, Z Li… - Frontiers in Cell and …, 2022 - frontiersin.org
Over the years, there has been a high demand for developing new safe and effective drug
carriers for cancer therapy. Emerging studies have indicated that exosomes can serve as …

A visible and colorimetric aptasensor based on DNA-capped single-walled carbon nanotubes for detection of exosomes

Y Xia, M Liu, L Wang, A Yan, W He, M Chen… - Biosensors and …, 2017 - Elsevier
Recently, many studies have shown the potential use of circulating exosomes as novel
biomarkers for monitoring and predicting a number of complex diseases, including cancer …