Cell Death and Survival Mechanisms in Cholangiocarcinogenesis

L D'Artista, M Seehawer - The American Journal of Pathology, 2024 - Elsevier
Cholangiocarcinoma (CAA) and other liver cancer subtypes often develop in damaged
organs. Physiologic agents or extrinsic factors like toxins can induce cell death in such …

Identification and validation of a novel ferroptosis-related gene signature for prognosis and potential therapeutic target prediction in cholangiocarcinoma

A Sae-Fung, A Mutirangura, S Jitkaew - Frontiers in Immunology, 2023 - frontiersin.org
Cholangiocarcinoma (CCA) is a highly heterogeneous and aggressive malignancy of the
bile ducts with a poor prognosis and high mortality rate. Effective targeted therapy and …

[HTML][HTML] Enhancing cholangiocarcinoma immunotherapy with adoptive T cells targeting HLA-restricted neoantigen peptides derived from driver gene mutations

A Panya, C Thepmalee, N Sawasdee… - Biomedicine & …, 2023 - Elsevier
Precision immunotherapy, driven by genomic and bioinformatic advancements, has
emerged as a promising and viable approach to combat cancer. Targeting neoantigens …

Molecular Profile and Prognostic Value of BAP1 Mutations in Intrahepatic Cholangiocarcinoma: A Genomic Database Analysis

A Rizzo, R Carloni, AD Ricci, A Di Federico… - Journal of Personalized …, 2022 - mdpi.com
Background. Recent years have witnessed the advent of molecular profiling for intrahepatic
cholangiocarcinoma (iCCA), and new techniques have led to the identification of several …

[HTML][HTML] MRTX1133 attenuates KRASG12D mutated-colorectal cancer progression through activating ferroptosis activity via METTL14/LINC02159/FOXC2 axis

J Zou, X Shi, Z Wu, S Zuo, X Tang, H Zhou… - Translational …, 2025 - Elsevier
Colorectal cancer (CRC) ranks as the third most commonly diagnosed cancer and the
second leading cause of cancer-related deaths worldwide. Studies have shown that CRC …