Research on psoriasis pathogenesis has largely increased knowledge on skin biology in
general. In the past 15 years, breakthroughs in the understanding of the pathogenesis of …

The pathogenesis of psoriasis can be explained by dysregulation of immunological cell
function as well as keratinocyte proliferation/differentiation. Recently, the immunological …

Background Generalized pustular psoriasis (GPP) is a rare, life-threatening, inflammatory
skin disease characterized by widespread eruption of sterile pustules. Interleukin-36 …

Pustular psoriasis (PP) is a group of inflammatory skin conditions characterized by infiltration
of neutrophil granulocytes in the epidermis to such an extent that clinically visible sterile …

Introduction: Generalized pustular psoriasis (GPP) is a rare, severe relapsing/remitting,
multisystem disease that can be difficult to treat. Recent clinical, histological, and genetic …

Generalized pustular psoriasis (GPP) is a rare auto‐inflammatory skin disease characterised
by acute episodes of sterile pustule formation. Diagnosis and treatment of the disease have …

Psoriasis is widely regarded as a multifactorial condition which is caused by the interaction
between inherited susceptibility alleles and environmental triggers. In the last decade …

Over recent years, significant progress has been made in characterisation of the underlying
pathogenic mechanisms in psoriasis, a common cutaneous disease that is associated with …

Background The term pustular psoriasis indicates a group of severe skin disorders
characterized by eruptions of neutrophil-filled pustules. The disease, which often manifests …

Theme issue: Psoriasis loci. Despite the complex correlation structure across the MHC due
to extensive linkage disequilibrium (Box 1)(16), HLA-C* 06: 02 is now confidently …