G protein-coupled receptors (GPCRs) are the largest single family of cell surface receptors
encoded by the human genome and they play pivotal roles in co-ordinating cellular systems …

The light sensor of vertebrate scotopic (low-light) vision, rhodopsin, is a G-protein-coupled
receptor comprising a polypeptide chain with bound chromophore, 11-cis-retinal, that …

Phosphorylation of G-protein-coupled receptors (GPCRs) by GPCR kinases (GRKs)
desensitizes G-protein signalling and promotes arrestin signalling, which is also modulated …

The development of robust architectures capable of large-scale fault-tolerant quantum
computation should consider both their quantum error-correcting codes and the underlying …

Tunable coupling of superconducting qubits has been widely studied due to its importance
for isolated gate operations in scalable quantum processor architectures. Here, we …

Opioids are used for pain management despite the side effects that contribute to the opioid
crisis. The pursuit of non-addictive opioid analgesics remains unattained due to the …

Abstract Type 2 diabetes (T2D) mellitus has emerged as a major global health concern that
has accelerated in recent years due to poor diet and lifestyle. Afflicted individuals have high …

The discovery of topological order has revised the understanding of quantum matter and
provided the theoretical foundation for many quantum error–correcting codes. Realizing …

Both CXC chemokine receptor 4 (CXCR4) and atypical chemokine receptor 3 (ACKR3) are
activated by the chemokine CXCL12 yet evoke distinct cellular responses. CXCR4 is a …

With conformation-specific nanobodies being used for a wide range of structural,
biochemical, and cell biological applications, there is a demand for antigen-binding …