Cerebral microbleeds: from depiction to interpretation

L Puy, M Pasi, M Rodrigues, SJ Van Veluw… - Journal of Neurology …, 2021 - jnnp.bmj.com
Cerebral microbleeds (CMBs) are defined as hypointense foci visible on T2*-weighted and
susceptible-weighted MRI sequences. CMBs are increasingly recognised with the …

European Stroke Organisation (ESO) guidelines on intravenous thrombolysis for acute ischaemic stroke

E Berge, W Whiteley, H Audebert… - European stroke …, 2021 - journals.sagepub.com
Intravenous thrombolysis is the only approved systemic reperfusion treatment for patients
with acute ischaemic stroke. These European Stroke Organisation (ESO) guidelines provide …

Intracranial bleeding after reperfusion therapy in acute ischemic stroke

G Charbonnier, L Bonnet, A Biondi, T Moulin - Frontiers in Neurology, 2021 - frontiersin.org
Intracranial hemorrhage is one of the most feared complications following brain infarct.
Ischemic tissues have a natural tendency to bleed. Moreover, the first recanalization trials …

Cerebral microbleeds and treatment effect of intravenous thrombolysis in acute stroke: an analysis of the WAKE-UP randomized clinical trial

L Schlemm, TB Braemswig, F Boutitie, J Vynckier… - Neurology, 2022 - AAN Enterprises
Background and Objectives Cerebral microbleeds (CMBs) are common in patients with
acute ischemic stroke and are associated with increased risk of intracerebral hemorrhage …

Fibrinogen depletion coagulopathy predicts major bleeding after thrombolysis for ischemic stroke: a multicenter study

M Romoli, L Vandelli, G Bigliardi, M Naccarato, J Moller… - Stroke, 2022 - Am Heart Assoc
Background: Symptomatic intracerebral hemorrhage (sICH) and major bleeding can be fatal
complications of intravenous thrombolysis (IVT) for acute ischemic stroke. We investigated …

Off-label use of intravenous thrombolysis for acute ischemic stroke: a critical appraisal of randomized and real-world evidence

G Tsivgoulis, O Kargiotis… - Therapeutic …, 2021 - journals.sagepub.com
Intravenous thrombolysis (IVT) represents the only systemic reperfusion therapy able to
reverse neurological deficit in patients with acute ischemic stroke (AIS). Despite its …

Cerebral small vessel disease and intracranial bleeding risk: Prognostic and practical significance

JG Best, A Jesuthasan… - International Journal of …, 2023 - journals.sagepub.com
Balancing the risks of recurrent ischemia and antithrombotic-associated bleeding,
particularly intracranial hemorrhage (ICH), is a key challenge in the secondary prevention of …

Microbleeds, cerebral hemorrhage, and functional outcome after endovascular thrombectomy

I Derraz, F Cagnazzo, N Gaillard, R Morganti… - Neurology, 2021 - AAN Enterprises
Objective To determine whether pretreatment cerebral microbleeds (CMBs) presence and
burden are correlated with an increased risk of intracranial hemorrhage (ICH) or poor …

Cerebral microbleeds load and long-term outcomes in minor ischemic stroke

K Sakuta, H Yaguchi, R Nakada, T Sato… - Journal of Stroke and …, 2021 - Elsevier
Abstract Background and Purpose The association between the cerebral microbleed (CMB)
count and outcomes in ischemic stroke has not been fully clarified. The aim of this study was …

Prevalence and impact of cerebral microbleeds on clinical and safety outcomes in acute ischaemic stroke patients receiving reperfusion therapy: A systematic review …

S Tipirneni, P Stanwell, R Weissert, SMM Bhaskar - Biomedicines, 2023 - mdpi.com
Background: Cerebral microbleeds (CMBs), a notable neuroimaging finding often
associated with cerebral microangiopathy, demonstrate a heightened prevalence in patients …