Differential diagnosis and workup of monocytosis: a systematic approach to a common hematologic finding

AA Mangaonkar, AJ Tande, DI Bekele - Current Hematologic Malignancy …, 2021 - Springer
Abstract Purpose of Review Monocytosis is a frequently encountered clinical condition that
needs appropriate investigation due to a broad range of differential diagnoses. This review …

Increasing recognition and emerging therapies argue for dedicated clinical trials in chronic myelomonocytic leukemia

A Renneville, MM Patnaik, O Chan, E Padron, E Solary - Leukemia, 2021 - nature.com
Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell disorder with
overlapping features of myelodysplastic syndromes (MDS) and myeloproliferative …

Plasmacytoid dendr itic cell expansion in myeloid neoplasms: A novel distinct subset of myeloid neoplasm?

J Peng, S He, X Yang, L Huang, J Wei - Critical Reviews in Oncology …, 2023 - Elsevier
Plasmacytoid dendritic cells (pDCs) are a specific dendritic cell type stemming from the
myeloid lineage. Clinically and pathologically, neoplasms associated with pDCs are …

Targeting amino acid metabolic vulnerabilities in myeloid malignancies

L Fultang, L Gneo, C De Santo, FJ Mussai - Frontiers in Oncology, 2021 - frontiersin.org
Tumor cells require a higher supply of nutrients for growth and proliferation than normal
cells. It is well established that metabolic reprograming in cancers for increased nutrient …

Plasmacytoid dendritic cells, a novel target in myeloid neoplasms

X Roussel, F Garnache Ottou, F Renosi - Cancers, 2022 - mdpi.com
Simple Summary Plasmacytoid dendritic cells are the main type I interferon producing cells
in humans and are able to modulate innate and adaptive immune responses. Tumor …

Contemporary risk stratification and treatment of chronic myelomonocytic leukemia

D Tremblay, N Rippel, J Feld, SM El Jamal… - The …, 2021 - academic.oup.com
Chronic myelomonocytic leukemia (CMML) is a hematologic malignancy characterized by
absolute monocytosis, one or more lineage dysplasia, and proliferative features including …

Phenotypic characterization of leukemia-initiating stem cells in chronic myelomonocytic leukemia

G Eisenwort, I Sadovnik, A Keller, D Ivanov, B Peter… - Leukemia, 2021 - nature.com
Chronic myelomonocytic leukemia (CMML) is a stem cell-derived neoplasm characterized
by dysplasia, uncontrolled expansion of monocytes, and substantial risk to transform to …

Multi-omic analysis of chronic myelomonocytic leukemia monocytes reveals metabolic and immune dysregulation leading to altered macrophage polarization

HM Addinsell, R Cant, NJ Hull, YH Wang… - Leukemia, 2025 - nature.com
Chronic myelomonocytic leukemia (CMML) is a clonal myelodysplastic/myeloproliferative
neoplasm characterized by persistent peripheral blood (PB) monocytosis with few effective …

[HTML][HTML] Chronic myelomonocytic leukemia: molecular pathogenesis and therapeutic innovations

L Marando, CM Csizmar, MM Patnaik - Haematologica, 2024 - pmc.ncbi.nlm.nih.gov
Chronic myelomonocytic leukemia (CMML) is an aggressive clonal stem cell disorder
categorized among myelodysplastic/myeloproliferative overlap neoplasms. While sharing …

Diagnostic features in paediatric MDS‐EB with UBTF‐internal tandem duplication: defining a unique subgroup

S Schwarz‐Furlan, C Gengler… - …, 2024 - Wiley Online Library
Aim Tandem‐duplications of the UBTF gene (UBTF‐TDs) have recently been identified as a
new genetic driver in young individuals with acute myeloid leukaemia (AML) and …