Hyperbranched polyglycerols: recent advances in synthesis, biocompatibility and biomedical applications

S Abbina, S Vappala, P Kumar, EMJ Siren… - Journal of Materials …, 2017 - pubs.rsc.org
In the pursuit of dendrimer alternatives, hyperbranched polymers have found increasing
interest from academia and industry in a broad range of fields due to their topological and …

Glycerol ether synthesis: A bench test for green chemistry concepts and technologies

M Sutter, ED Silva, N Duguet, Y Raoul, E Métay… - Chemical …, 2015 - ACS Publications
Naturally occurring, glycerol ethers are generally pure enantiomers, and batylic, chimylic,
and selachylic alcohols (Scheme 1) are the major ones which can be found in lipid …

Polyglycerols as multi-functional platforms: synthesis and biomedical applications

P Pouyan, M Cherri, R Haag - Polymers, 2022 - mdpi.com
The remarkable and unique characteristics of polyglycerols (PG) have made them an
attractive candidate for many applications in the biomedical and pharmaceutical fields. The …

Blood circulation of soft nanomaterials is governed by dynamic remodeling of protein opsonins at nano-biointerface

S Abbina, LE Takeuchi, P Anilkumar, K Yu… - Nature …, 2020 - nature.com
Nanomaterials in the blood must mitigate the immune response to have a prolonged
vascular residency in vivo. The composition of the protein corona that forms at the nano …

An Ultrahydrating Polymer that Protects Protein Therapeutics and RNA‐Lipid Nanoparticles Against Freezing, Heat and Lyophilization Stress

A Herrmann, S Abbina, NV Bathula… - Advanced Functional …, 2024 - Wiley Online Library
RNA and protein‐based therapeutics constitute almost half of recent drug approvals and
receive considerable attention within biotechnology industries. Ensuring their stability and …

Linear polysialoside outperforms dendritic analogs for inhibition of influenza virus infection in vitro and in vivo

S Bhatia, D Lauster, M Bardua, K Ludwig… - Biomaterials, 2017 - Elsevier
Inhibition of influenza A virus infection by multivalent sialic acid inhibitors preventing viral
hemagglutinin binding to host cells of the respiratory tract is a promising strategy. However …

Hyperbranched polyglycerol nanostructures for anti-biofouling, multifunctional drug delivery, bioimaging and theranostic applications

M Jafari, SS Abolmaali, H Najafi… - International journal of …, 2020 - Elsevier
Nowadays, great attention has been paid to the design and development of novel
macromolecular constructions in drug delivery. Hyperbranched polymers (HBPs) are …

Power of the disulfide bond: an ideal random copolymerization of biodegradable redox-responsive hyperbranched polyglycerols

M Cherri, JF Romero, L Steiner, M Dimde… - …, 2023 - ACS Publications
The development of copolymerization techniques that can randomly incorporate
biodegradable moieties into the hyperbranched polyglycerol backbone is an option to …

Redox-degradable biocompatible hyperbranched polyglycerols: synthesis, copolymerization kinetics, degradation, and biocompatibility

S Son, E Shin, BS Kim - Macromolecules, 2015 - ACS Publications
Polymers that are biocompatible and degrade in response to stimuli are highly desirable as
smart drug-delivery carriers. We report the first novel redox-degradable hyperbranched …

Green synthesis of hyperbranched polyglycerol at room temperature

E Mohammadifar, A Bodaghi… - ACS Macro …, 2017 - ACS Publications
In this work we report on a new method for the cationic polymerization of glycidol by citric
acid at ambient and solvent free conditions. In this polymerization, citric acid is a proton …