CASP (critical assessment of structure prediction) assesses the state of the art in modeling
protein structure from amino acid sequence. The most recent experiment (CASP13 held in …

The molecular details involved in the folding, dynamics, organization, and interaction of
proteins with other molecules are often difficult to assess by experimental techniques …

While AlphaFold2 can predict accurate protein structures from the primary sequence,
challenges remain for proteins that undergo conformational changes or for which few …

Critical assessment of structure prediction (CASP) is a community experiment to advance
methods of computing three‐dimensional protein structure from amino acid sequence. Core …

Crosslinking mass spectrometry has become a core technology in structural biology and is
expanding its reach towards systems biology. Its appeal lies in a rapid workflow, high …

Microorganisms rely on protein interactions to transmit signals, react to stimuli, and grow.
One of the best ways to understand these protein interactions is through structural …

Structural biology is entering an exciting time where many new high-resolution structures of
large complexes and membrane proteins are determined regularly. These advances have …

We present the assembly category assessment in the 13th edition of the CASP community‐
wide experiment. For the second time, protein assemblies constitute an independent …

A goal of structural biology is to understand how macromolecules carry out their biological
roles by identifying their metastable states, mechanisms of action, pathways leading to …

The structural and dynamical characterization of biomolecules holds central importance in
the endeavor to understand the molecular mechanisms regulating living systems. However …