Combination of drug and stem cells neurotherapy: potential interventions in neurotrauma and traumatic brain injury

K Zibara, N Ballout, S Mondello, N Karnib… - …, 2019 - Elsevier
Traumatic brain injury (TBI) has been recognized as one of the major public health issues
that leads to devastating neurological disability. As a consequence of primary and …

The cell-based approach in neurosurgery: Ongoing trends and future perspectives

S Luzzi, AM Crovace, M Del Maestro, AG Lucifero… - Heliyon, 2019 - cell.com
Objective Examination of the current trends and future perspectives of the cell-based
therapies in neurosurgery. Methods A PubMed/MEDLINE-based systematic review has …

Neural stem cell therapy in conjunction with curcumin loaded in niosomal nanoparticles enhanced recovery from traumatic brain injury

A Narouiepour, A Ebrahimzadeh-Bideskan… - Scientific Reports, 2022 - nature.com
Despite a great amount of effort, there is still a need for reliable treatments of traumatic brain
injury (TBI). Recently, stem cell therapy has emerged as a new avenue to address neuronal …

Traumatic brain injury and stem cell: pathophysiology and update on recent treatment modalities

C Reis, V Gospodarev, H Reis… - Stem cells …, 2017 - Wiley Online Library
Traumatic brain injury (TBI) is a complex condition that presents with a wide spectrum of
clinical symptoms caused by an initial insult to the brain through an external mechanical …

Altered hippocampal neurogenesis during the first 7 days after a fluid percussion traumatic brain injury

LA Shapiro - Cell transplantation, 2017 - journals.sagepub.com
Traumatic brain injury (TBI) is a devastating disorder causing negative outcomes in millions
of people each year. Despite the alarming number of brain injuries and the long-term …

Future perspectives in spinal cord repair: brain as saviour? TSCI with concurrent TBI: pathophysiological interaction and impact on MSC treatment

P Köhli, E Otto, D Jahn, MJ Reisener, J Appelt… - Cells, 2021 - mdpi.com
Traumatic spinal cord injury (TSCI), commonly caused by high energy trauma in young
active patients, is frequently accompanied by traumatic brain injury (TBI). Although …

Amelioration of penetrating ballistic-like brain injury induced cognitive deficits after neuronal differentiation of transplanted human neural stem cells

MS Spurlock, AI Ahmed, KN Rivera… - Journal of …, 2017 - liebertpub.com
Penetrating traumatic brain injury (PTBI) is one of the major cause of death and disability
worldwide. Previous studies with penetrating ballistic-like brain injury (PBBI), a PTBI rat …

A three-dimensional matrix system containing melatonin and neural stem cells repairs damage from traumatic brain injury in rats

XY Fang, DW Zhao, C Zhang, HF Ge… - Neural regeneration …, 2022 - journals.lww.com
Brain lesions can cause neural stem cells to activate, proliferate, differentiate, and migrate to
the injured area. However, after traumatic brain injury, brain tissue defects and …

[HTML][HTML] Loading neural stem cells on hydrogel scaffold improves cell retention rate and promotes functional recovery in traumatic brain injury

T Chen, Y Xia, L Zhang, T Xu, Y Yi, J Chen, Z Liu… - Materials Today Bio, 2023 - Elsevier
Neural stem cell (NSC) has gained considerable attention in traumatic brain injury (TBI)
treatment because of their ability to replenish dysfunctional neurons and stimulate …

DPYSL2 is a novel regulator for neural stem cell differentiation in rats: revealed by Panax notoginseng saponin administration

LL Xiong, DL Qiu, GH Xiu, M Al-Hawwas… - Stem Cell Research & …, 2020 - Springer
Background The limited neuronal differentiation of the endogenous or grafted neural stem
cells (NSCs) after brain injury hampers the clinic usage of NSCs. Panax notoginseng …