• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Importance Patient-reported outcomes are increasingly used as end points in clinical trials,
assessments in clinical care, and tools for population health, with an increasing role in …

Abstract Aim The “2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management
of Patients With Chronic Coronary Disease” provides an update to and consolidates new …

The Shock Academic Research Consortium is a multi-stakeholder group, including
representatives from the US Food and Drug Administration and other government agencies …

Aims Oxygen-pulse morphology and gas exchange analysis measured during
cardiopulmonary exercise testing (CPET) has been associated with myocardial ischaemia …

Smart devices are a fundamental media for acquisition, processing, storage, and transfer of
digital health data. The global penetration and high frequency usage of smart devices such …

Percutaneous coronary intervention (PCI) is frequently performed for stable angina.
However, the first blinded trial, ORBITA, did not show a placebo-controlled increment in …

Background Growing evidence for coronary stents in patients with stable coronary artery
disease (CAD) suggests that the benefits of stents are uncertain. The goal of this study was …

Objective To assess the frequency, change in prevalence, and prognostic significance of
dyspnea among contemporary patients referred for cardiac stress testing. Patients and …

The clinical history elicited during the patient visit is traditionally viewed as the most
important source of medical information, 1, 2 particularly for patients with heart failure. 3 As …