Glutamate and gamma-aminobutyric acid systems in the pathophysiology of major depression and antidepressant response to ketamine

MS Lener, MJ Niciu, ED Ballard, M Park, LT Park… - Biological …, 2017 - Elsevier
In patients with major depressive disorder or bipolar disorder, abnormalities in excitatory
and/or inhibitory neurotransmission and neuronal plasticity may lead to aberrant functional …

[HTML][HTML] Rumination in major depressive and bipolar disorder–a meta-analysis

LN Kovács, ZK Takacs, Z Tóth, E Simon… - Journal of affective …, 2020 - Elsevier
Background rumination, defined as repetitive thoughts about emotionally relevant
experiences, has been linked extensively with mood disorders, especially major depressive …

Mindfulness-based cognitive therapy for bipolar disorder: A systematic review

DA Lovas, Z Schuman-Olivier - Journal of affective disorders, 2018 - Elsevier
Background Persisting high levels of relapse, morbidity and mortality in bipolar disorder
(BD) in spite of first-line, evidence-based psychopharmacology has spurred development …

Associations between cannabis use, cannabis use disorder, and mood disorders: longitudinal, genetic, and neurocognitive evidence

L Kuhns, E Kroon, K Colyer-Patel, J Cousijn - Psychopharmacology, 2022 - Springer
Rationale Cannabis use among people with mood disorders increased in recent years.
While comorbidity between cannabis use, cannabis use disorder (CUD), and mood …

Therapeutic mechanisms of lithium in bipolar disorder: recent advances and current understanding

GS Malhi, T Outhred - CNS drugs, 2016 - Springer
Lithium is the most effective and well established treatment for bipolar disorder, and it has a
broad array of effects within cellular pathways. However, the specific processes through …

Impact of childhood trauma on cognitive profile in bipolar disorder

E Jiménez, B Solé, B Arias, M Mitjans, C Varo… - Bipolar …, 2017 - Wiley Online Library
Objectives Bipolar Disorder (BD) is associated with cognitive impairment even during
remission periods. Nonetheless, this impairment seems to adjust to different profiles of …

A pilot, open‐label, 8‐week study evaluating the efficacy, safety and tolerability of adjunctive minocycline for the treatment of bipolar I/II depression

JK Soczynska, SH Kennedy, M Alsuwaidan… - Bipolar …, 2017 - Wiley Online Library
Objectives The objectives of the study were to determine if adjunctive minocycline mitigates
depressive symptom severity and improves cognitive function in individuals with bipolar I/II …

On the relationship between mind wandering and mindfulness

A Belardi, L Chaieb, A Rey-Mermet, F Mormann… - scientific reports, 2022 - nature.com
Mind wandering (MW) and mindfulness have both been reported to be vital moderators of
psychological wellbeing. Here, we aim to examine how closely associated these …

Cognition in depression: Can we THINC-it better?

BT Baune, GS Malhi, G Morris, T Outhred… - Journal of Affective …, 2018 - Elsevier
Background Cognitive compromise is a common experience for patients with depression
and other mood disorders. Depressed patients sustain deficits in working memory and …

AMPA receptors mediate the pro-cognitive effects of electrical and optogenetic stimulation of the medial prefrontal cortex in antidepressant non-responsive Wistar …

M Papp, P Gruca, M Lason, E Litwa… - Journal of …, 2020 - journals.sagepub.com
Background: The chronic mild stress (CMS) procedure is a widely used animal model of
depression, and its application in Wistar–Kyoto (WKY) rats has been validated as a model of …