BDNF as a promising therapeutic agent in Parkinson's disease

E Palasz, A Wysocka, A Gasiorowska… - International journal of …, 2020 - mdpi.com
Brain-derived neurotrophic factor (BDNF) promotes neuroprotection and neuroregeneration.
In animal models of Parkinson's disease (PD), BDNF enhances the survival of dopaminergic …

[HTML][HTML] Brain-derived neurotrophic factor: a key molecule for memory in the healthy and the pathological brain

M Miranda, JF Morici, MB Zanoni… - Frontiers in cellular …, 2019 - frontiersin.org
Brain Derived Neurotrophic Factor (BDNF) is a key molecule involved in plastic changes
related to learning and memory. The expression of BDNF is highly regulated, and can lead …

[HTML][HTML] Effect of aerobic exercise on hippocampal volume in humans: a systematic review and meta-analysis

J Firth, B Stubbs, D Vancampfort, F Schuch… - Neuroimage, 2018 - Elsevier
Hippocampal volume increase in response to aerobic exercise has been consistently
observed in animal models. However, the evidence from human studies is equivocal. We …

[PDF][PDF] Brain-derived neurotrophic factor and its clinical implications

S Bathina, UN Das - Archives of medical science, 2015 - termedia.pl
Brain-derived neurotrophic factor (BDNF) plays an important role in neuronal survival and
growth, serves as a neurotransmitter modulator, and participates in neuronal plasticity …

A meta-analytic review of the effects of exercise on brain-derived neurotrophic factor

KL Szuhany, M Bugatti, MW Otto - Journal of psychiatric research, 2015 - Elsevier
Consistent evidence indicates that exercise improves cognition and mood, with preliminary
evidence suggesting that brain-derived neurotrophic factor (BDNF) may mediate these …

[HTML][HTML] The involvement of BDNF, NGF and GDNF in aging and Alzheimer's disease

J Budni, T Bellettini-Santos, F Mina, ML Garcez… - Aging and …, 2015 - ncbi.nlm.nih.gov
Aging is a normal physiological process accompanied by cognitive decline. This aging
process has been the primary risk factor for development of aging-related diseases such as …

Effects of neurotrophic factors in glial cells in the central nervous system: expression and properties in neurodegeneration and injury

S Pöyhönen, S Er, A Domanskyi… - Frontiers in physiology, 2019 - frontiersin.org
Astrocytes, oligodendrocytes, and microglia are abundant cell types found in the central
nervous system and have been shown to play crucial roles in regulating both normal and …

Depression and risk of developing dementia

AL Byers, K Yaffe - Nature Reviews Neurology, 2011 - nature.com
Depression is highly common throughout the life course and dementia is common in late life.
Depression has been linked with dementia, and growing evidence implies that the timing of …

Physical exercise as a preventive or disease-modifying treatment of dementia and brain aging

JE Ahlskog, YE Geda, NR Graff-Radford… - Mayo clinic …, 2011 - Elsevier
A rapidly growing literature strongly suggests that exercise, specifically aerobic exercise,
may attenuate cognitive impairment and reduce dementia risk. We used PubMed (keywords …

The neuropathology of sport

AC McKee, DH Daneshvar, VE Alvarez, TD Stein - Acta neuropathologica, 2014 - Springer
The benefits of regular exercise, physical fitness and sports participation on cardiovascular
and brain health are undeniable. Physical activity reduces the risk for cardiovascular …