Two hormones for one receptor: evolution, biochemistry, actions, and pathophysiology of LH and hCG

L Casarini, D Santi, G Brigante, M Simoni - Endocrine reviews, 2018 - academic.oup.com
LH and chorionic gonadotropin (CG) are glycoproteins fundamental to sexual development
and reproduction. Because they act on the same receptor (LHCGR), the general consensus …

Aspects of common marmoset basic biology and life history important for biomedical research

DH Abbott, DK Barnett, RJ Colman… - Comparative …, 2003 - ingentaconnect.com
While common marmosets are increasingly used as alternative primate models in
biomedical research, their life history, specialized behavior and unique physiology are not …

Accelerated maturation of primate testis by xenografting into mice

A Honaramooz, MW Li, MCT Penedo… - Biology of …, 2004 - academic.oup.com
Testicular maturation and sperm production throughout the life of the male form the basis of
male fertility. It is difficult to elucidate the intricate processes controlling testicular maturation …

Human LH and hCG stimulate differently the early signalling pathways but result in equal testosterone synthesis in mouse Leydig cells in vitro

L Riccetti, F De Pascali, L Gilioli, F Potì, LB Giva… - Reproductive Biology …, 2017 - Springer
Background Human luteinizing hormone (LH) and chorionic gonadotropin (hCG) are
glycoprotein hormones regulating development and reproductive functions by acting on the …

[HTML][HTML] Recent advances in understanding gonadotropin signaling

L Casarini, M Simoni - Faculty reviews, 2021 - ncbi.nlm.nih.gov
Gonadotropins are glycoprotein sex hormones regulating development and reproduction
and bind to specific G protein–coupled receptors expressed in the gonads. Their effects on …

Structural and functional plasticity of the luteinizing hormone/choriogonadotrophin receptor

B Troppmann, G Kleinau, G Krause… - Human reproduction …, 2013 - academic.oup.com
BACKGROUND In recent years it became evident that several types of the luteinizing
hormone/choriogonadotrophin receptor (LHCGR) exist. In addition to the classical receptor …

[图书][B] Nonhuman primates in biomedical research: biology and management

CR Abee, K Mansfield, SD Tardif, T Morris - 2012 - books.google.com
The second edition of this text provides a comprehensive, up-to-date review of the use of
nonhuman primates in biomedical research. The publication emphasizes the biology and …

Physiology and endocrinology of the ovarian cycle in macaques

GF Weinbauer, M Niehoff, M Niehaus… - Toxicologic …, 2008 - journals.sagepub.com
Macaques provide excellent models for preclinical testing and safety assessment of female
reproductive toxicants. Currently, cynomolgus monkeys are the predominant species for …

Estrogen modulates specific life and death signals induced by LH and hCG in human primary granulosa cells in vitro

L Casarini, L Riccetti, F De Pascali, L Gilioli… - International Journal of …, 2017 - mdpi.com
Luteinizing hormone (LH) and human chorionic gonadotropin (hCG) are glycoprotein
hormones used for assisted reproduction acting on the same receptor (LHCGR) and …

Male minipuberty in human and non-human primates: planting the seeds of future fertility

AS Busch, JM Paturlanne, N Neuhaus… - …, 2023 - rep.bioscientifica.com
In brief Minipuberty is a transient activity period of the hypothalamic–pituitary–gonadal axis
in the postnatal and infant period including surging serum concentrations of reproductive …