Umbelliferone and its synthetic derivatives as suitable molecules for the development of agents with biological activities: a review of their pharmacological and …
A Kornicka, Ł Balewski, M Lahutta, J Kokoszka - Pharmaceuticals, 2023 - mdpi.com
Umbelliferone (UMB), known as 7-hydroxycoumarin, hydrangine, or skimmetine, is a
naturally occurring coumarin in the plant kingdom, mainly from the Umbelliferae family that …
naturally occurring coumarin in the plant kingdom, mainly from the Umbelliferae family that …
Chitosan/HPMC-based mucoadhesive film co-loaded with fluconazole and ofloxacin for management of polymicrobial keratitis
Bacterial and fungal co-infection leads to polymicrobial keratitis (PMK). The current study
produced swellable mucoadhesive biopolymeric films composed of chitosan, HPMC, and …
produced swellable mucoadhesive biopolymeric films composed of chitosan, HPMC, and …
The preparation of lipid-based drug delivery system using melt extrusion
A major focus of pharmaceutical product development process is enhancing the
bioavailability of a poorly water-soluble compound [ie, a Biopharmaceutics Classification …
bioavailability of a poorly water-soluble compound [ie, a Biopharmaceutics Classification …
Folate decorated lipid chitosan hybrid nanoparticles of 5-fluorouracil for enhanced anticancer efficacy against colon cancer
The study aimed to develop folate decorated lipid chitosan hybrid nanoparticles for targeted
delivery of 5-fluorouracil in colon cancer by utilizing the overexpressed folate receptors on …
delivery of 5-fluorouracil in colon cancer by utilizing the overexpressed folate receptors on …
Lipid poly (ɛ-caprolactone) hybrid nanoparticles of 5-fluorouracil for sustained release and enhanced anticancer efficacy
Aims The present study aimed to develop and characterize poly (ɛ-caprolactone)(PCL)
based lipid polymer hybrid nanoparticles for sustained delivery and in-vitro anti-cancer …
based lipid polymer hybrid nanoparticles for sustained delivery and in-vitro anti-cancer …
Phospholipid complex-loaded self-assembled phytosomal soft nanoparticles: evidence of enhanced solubility, dissolution rate, ex vivo permeability, oral bioavailability …
DR Telange, NK Sohail, AT Hemke, PS Kharkar… - Drug Delivery and …, 2021 - Springer
In this study, self-assembled phytosomal soft nanoparticles encapsulated with phospholipid
complex (MPLC SNPs) using a combination of solvent evaporation and nanoprecipitation …
complex (MPLC SNPs) using a combination of solvent evaporation and nanoprecipitation …
Exploring the inclusion complex of a drug (umbelliferone) with α-cyclodextrin optimized by molecular docking and increasing bioavailability with minimizing the doses …
In this study, umbelliferone and α-cyclodextrin host molecules have been mixed up through
a coprecipitation method to prepare a supramolecular complex to provide physical insights …
a coprecipitation method to prepare a supramolecular complex to provide physical insights …
Development and Characterization of Pentaerythritol-EudragitRS100 Co-processed Excipients as Solid Dispersion Carriers for Enhanced Aqueous Solubility, In Vitro …
DR Telange, NM Bhaktani, AT Hemke, AM Pethe… - ACS …, 2023 - ACS Publications
Atorvastatin (ATV), a lipid-lowering agent, has low oral bioavailability due to its poor water
solubility, permeability, and low dissolution rate. Therefore, pentaerythritol-EudragitRS100 …
solubility, permeability, and low dissolution rate. Therefore, pentaerythritol-EudragitRS100 …
The optimization of a dimenhydrinate transdermal patch formulation based on the quantitative analysis of in vitro release data by DDSolver through skin penetration …
BK Abdul Rasool, AA Mohammed, YY Salem - Scientia Pharmaceutica, 2021 - mdpi.com
Dimenhydrinate is an over-the-counter medication that is used to relieve nausea, vomiting,
and vertigo caused by motion sickness. It has a short elimination half-life, possibly due to its …
and vertigo caused by motion sickness. It has a short elimination half-life, possibly due to its …
Development of phospholipon® 90H complex nanocarrier with enhanced oral bioavailability and anti-inflammatory potential of genistein
Abstract Genistein (GEN), an isoflavonoid, offers multifunctional biological activities.
However, its poor oral bioavailability, aqueous solubility, extensive metabolism, and short …
However, its poor oral bioavailability, aqueous solubility, extensive metabolism, and short …