[HTML][HTML] Phytochemicals in drug discovery—a confluence of tradition and innovation

P Chihomvu, A Ganesan, S Gibbons… - International journal of …, 2024 - mdpi.com
Phytochemicals have a long and successful history in drug discovery. With recent
advancements in analytical techniques and methodologies, discovering bioactive leads from …

[HTML][HTML] Bioactivity and bioavailability of carotenoids applied in human health: Technological advances and innovation

TG Bas - International Journal of Molecular Sciences, 2024 - mdpi.com
This article presents a groundbreaking perspective on carotenoids, focusing on their
innovative applications and transformative potential in human health and medicine …

Recent trends and therapeutic potential of phytoceutical‐based nanoparticle delivery systems in mitigating non‐small cell lung cancer

A Haysom‐McDowell, KR Paudel, S Yeung… - Molecular …, 2024 - Wiley Online Library
Lung cancer is the leading cause of cancer death globally, with non‐small cell lung cancer
accounting for the majority (85%) of cases. Standard treatments including chemotherapy …

Microbiome-mucosal immunity nexus: driving forces in respiratory disease progression

YC Park, SY Choi, Y Cha, HW Yoon, YM Son - Journal of Microbiology, 2024 - Springer
The importance of the complex interplay between the microbiome and mucosal immunity,
particularly within the respiratory tract, has gained significant attention due to its potential …

Empowering lung cancer treatment: Harnessing the potential of natural phytoconstituent‐loaded nanoparticles

T Siddiquee, NA Bhaskaran, K Nathani… - Phytotherapy …, 2024 - Wiley Online Library
Lung cancer, the second leading cause of cancer‐related deaths, accounts for a substantial
portion, representing 18.4% of all cancer fatalities. Despite advances in treatment modalities …

Metabolite Profiling of Colvillea racemosa via UPLC-ESI-QTOF-MS Analysis in Correlation to the In Vitro Antioxidant and Cytotoxic Potential against A549 Non-Small …

Á Fernández-Ochoa, IY Younis, RK Arafa… - Plants, 2024 - mdpi.com
In this study, flower and leaf extracts of Colvillea racemosa were considered a source of
bioactive compounds. In this context, the objective of the study focused on investigating the …

Molecular mechanisms involved in therapeutic effects of natural compounds against cisplatin-induced cardiotoxicity: a review

M Hesari, P Mohammadi, M Moradi… - Naunyn-Schmiedeberg's …, 2024 - Springer
Cisplatin is a widely used chemotherapeutic agent for the treatment of various cancers.
However, the clinical use of cisplatin is limited by its cardiotoxic side effects. The primary …

Allicin: a promising modulator of apoptosis and survival signaling in cancer

S Bhuker, A Kaur, K Rajauria, HS Tuli, AK Saini… - Medical Oncology, 2024 - Springer
Abstract According to the World Health Organization, cancer is the foremost cause of
mortality globally. Various phytochemicals from natural sources have been extensively …

[HTML][HTML] Genetic Blueprints in Lung Cancer: Foundations for Targeted Therapies

A Dan, LM Burtavel, MC Coman, IO Focsa… - …, 2024 - pmc.ncbi.nlm.nih.gov
This article provides a comprehensive overview of lung cancer from a genetic perspective,
emphasizing the molecular pathways involved in its pathogenesis. This review presents the …

[HTML][HTML] Targeting PI3K/AKT/mTOR Signalling pathway in non-small-cell lung carcinoma: Exploring promising bioactive natural compounds as anti-cancer agents

AN Khan, RD Jawarkar, MEA Zaki, AA Al Mutairi… - Chemical Physics …, 2024 - Elsevier
Lung cancer has become the most common solid tumor and the leading cause of cancer-
related deaths worldwide. It is estimated that the annual mortality rate for lung cancer is 1.8 …