Pulling the strings on solid-to-liquid phase transitions in cell collectives

D Pinheiro, J Mitchel - Current Opinion in Cell Biology, 2024 - Elsevier
Cell collectives must dynamically adapt to different biological contexts. For instance, in
homeostatic conditions, epithelia must establish a barrier between body compartments and …

Ductile-to-brittle transition and yielding in soft amorphous materials: perspectives and open questions

T Divoux, E Agoritsas, S Aime, C Barentin, JL Barrat… - Soft Matter, 2024 - pubs.rsc.org
Soft amorphous materials are viscoelastic solids ubiquitously found around us, from clays
and cementitious pastes to emulsions and physical gels encountered in food or biomedical …

Changes in tissue fluidity predict tumor aggressiveness in vivo

F Sauer, S Grosser, M Shahryari, A Hayn… - Advanced …, 2023 - Wiley Online Library
Cancer progression is caused by genetic changes and associated with various alterations in
cell properties, which also affect a tumor's mechanical state. While an increased stiffness …

Effect of non-linear strain stiffening in eDAH and unjamming

X Xie, F Sauer, S Grosser, J Lippoldt, E Warmt, A Das… - Soft Matter, 2024 - pubs.rsc.org
In cell clusters, the prominent factors at play encompass contractility-based enhanced tissue
surface tension and cell unjamming transition. The former effect pertains to the boundary …

[HTML][HTML] Parallel on-chip micropipettes enabling quantitative multiplexed characterization of vesicle mechanics and cell aggregates rheology

S Landiech, M Elias, P Lapèze, H Ajiyel… - APL …, 2024 - pubs.aip.org
Micropipette aspiration (MPA) is one of the gold standards for quantifying biological
samples' mechanical properties, which are crucial from the cell membrane scale to the …

A shape-driven reentrant jamming transition in confluent monolayers of synthetic cell-mimics

P Arora, S Sadhukhan, SK Nandi, D Bi… - Nature …, 2024 - nature.com
Many critical biological processes, like wound healing, require densely packed cell
monolayers/tissues to transition from a jammed solid-like to a fluid-like state. Although …

Emergent phenomena in chiral active matter

J Mecke, JO Nketsiah, R Li, Y Gao - National Science Open, 2024 - nso-journal.org
In recent years, there has been growing interest in the study of chiral active materials, which
consist of building blocks that show active dynamics featuring chiral symmetry breaking, eg …

Rejuvenation and memory effects in active glasses induced by thermal and active cycling

G Janzen, LMC Janssen - Physical Review Research, 2024 - APS
It has recently been shown that thermal active glasses can display physical aging behavior
comparable to that of passive glasses, although there are some notable distinctions due to …

Viscoelastic properties of colorectal liver metastases reflect tumour cell viability

LM Skrip, S Moosburner, P Tang, J Guo… - Journal of Translational …, 2024 - Springer
Background Colorectal cancer is the third most common tumour entity in the world and up to
50% of the patients develop liver metastases (CRLM) within five years. To improve and …

[HTML][HTML] Sensitivity of magnetic resonance elastography to extracellular matrix and cell motility in human prostate cancer cell line-derived xenograft models

A Kader, J Snellings, LC Adams, P Gottheil… - Biomaterials …, 2024 - Elsevier
Prostate cancer (PCa) is a significant health problem in the male population of the Western
world. Magnetic resonance elastography (MRE), an emerging medical imaging technique …