Biomolecular interactions underpin most processes inside the cell. Hence, a precise and
quantitative understanding of molecular association and dissociation events is crucial, not …

The four syndecans identified in mammals are membrane proteoglycans that play major
roles in regulating cell behavior, cell signaling, and cell‐matrix interactions. The membrane …

Proteins are major drug targets, and drug–target interaction identification and analysis are
important factors for drug discovery. Atomic force microscopy (AFM) is a powerful tool …

Protein–protein interactions (PPIs) between the B-cell lymphoma 2 (Bcl-2) family are
considered a major driving force in cell cycle regulation and signaling. However, how this …

Single-molecule studies can reveal the distribution of states and interactions between ligand–
enzyme complexes not accessible for most studies that measure a large ensemble average …

The knowledge on how cells interact with microenvironment is particularly important in
understanding the interaction of cancer cells with surrounding stroma, which affects cell …

Purpose Epithelial–mesenchymal (EMT) transition plays an important role in metastasis and
is accompanied by an upregulation of N-cadherin expression. A new nanoparticulate system …

Detailed knowledge of intramolecular hydrogen bonds, including their nanomechanics, in a
peptide secondary structure is crucial for understanding mechanisms of numerous …

Cation-π interaction is an electrostatic interaction between a cation and an electron-rich
arene. It plays an essential role in many biological systems as a vital driving force for protein …

Lectin–carbohydrate interactions can be exploited in ultrasensitive biochemical recognition
or medical diagnosis. For this purpose, besides the high specificity of the interactions, an …